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MABS487 Anti-Modified Citrulline Antibody, clone C4

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MABS487
100 µL  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      AWB, ELISAHuman RecombinantPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABS487
      DescriptionAnti-Modified Citrulline Antibody, clone C4
      Alternate Names
      • citrulline
      • modified citrulline
      Background InformationCitrulline is thought to be an unincorporated amino acid that plays a part in intermediary metabolism. It is produced in the small intestine by enterocytes. Citrulline concentration in plasma and serum is thought to be a reliable and noninvasive biomarker of small intestine function and mass during disease. Citrulline has also been shown to play an important role in protein homeostasis. Modified citrulline is a chemically modified form of citrulline that is more immunogenic.
      References
      Product Information
      FormatPurified
      PresentationHuman recombinant monoclonal IgG1λ in buffer containing PBS with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Modified Citrulline Antibody is validated for use in Western blotting and ELISA for the detection of Modified Citrulline.
      Key Applications
      • Western Blotting
      • ELISA
      Application NotesWestern Blotting Analysis: A 1:1,000 dilution from a representative lot detected Modified Citrulline in 10 µg of treated HL-60 cell lysate, using Anti-Human secondary antibody.
      ELISA Analysis: A representative lot detected Modified Citrulline in ELISA.
      Biological Information
      ImmunogenCitrulline-containing peptide modified with 2,3-butanedione monoxime and antipyrine.
      CloneC4
      ConcentrationPlease refer to lot specific datasheet.
      HostHuman Recombinant
      IsotypeIgG1λ
      Species Reactivity
      • All
      Antibody TypeMonoclonal Antibody
      Purification MethodProtein A Purfied
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in treated cornified human cell lysate.

      Western Blotting Analysis: A 1:1,000 dilution of this antibody detected Modified Citrulline in 10 µg of treated cornified human cell lysate, using Anti-Human secondary antibody.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABS487 04055977158878

      Documentation

      Anti-Modified Citrulline Antibody, clone C4 SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Modified Citrulline Antibody, clone C4 Certificates of Analysis

      TitleLot Number
      Anti-Modified Citrulline, clone C4 3068537
      Anti-Modified Citrulline, clone C4 - 3159551 3159551
      Anti-Modified Citrulline, clone C4 - 3169851 3169851
      Anti-Modified Citrulline, clone C4 - 3193848 3193848
      Anti-Modified Citrulline, clone C4 - 3284333 3284333
      Anti-Modified Citrulline, clone C4 - 3318418 3318418
      Anti-Modified Citrulline, clone C4 - 3407336 3407336
      Anti-Modified Citrulline, clone C4 - 3463633 3463633
      Anti-Modified Citrulline, clone C4 - 3492223 3492223
      Anti-Modified Citrulline, clone C4 - 3508396 3508396

      Brochure

      Title
      NPI Flyer- Epigenetics and Nuclear Function Feature
      New Products - Antibodies, Small Molecule, Inhibitors

      Technical Info

      Title
      White Paper: Further considerations of antibody validation and usage.