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438192 Anti-LRP, Light Chain Mouse mAb (5A6)

This Anti-LRP, Light Chain Mouse mAb (5A6) is validated for use in Frozen Sections, Immunoblotting, Paraffin Sections for the detection of LRP, Light Chain.

Anti-LRP, Light Chain Mouse mAb (5A6) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-Low Density Lipoprotein Receptor-Related Protein

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438192
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Overview

Replacement Information

Key Spec Table

Species ReactivityHostAntibody Type
H, M, RbMMonoclonal Antibody

Pricing & Availability

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438192-100UGCN
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      		 Plastic ampoule 100 μg
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      Description
      OverviewRecognizes the ~85 kDa LRP protein.
      Catalogue Number438192
      Brand Family Calbiochem®
      SynonymsAnti-Low Density Lipoprotein Receptor-Related Protein
      Application Data
      Detection of light chain LRP by immunoblotting. Samples: Soluble LRP at 500 ng (lane 1) and 50 ng (lane 2) with prestained standard (lane 3). Primary antibody: Anti-LRP, Light Chain Mouse mAb (5A6) (Cat. No. 438192) (1 µg/ml). Detection: chemiluminescence.
      References
      ReferencesMikhailenko, I., et al. 2001. J. Biol. Chem. 276, 39484.
      Rebeck, W.G., et al. 2001. Mol. Brain Res. 87, 238.
      Coukos, G., et al. 1994. Am. J. Pathol. 144, 383.
      Daugherty, A., and Rateri, D.L. 1994. Arterioscler Thromb. 14, 2017.
      Strickland, D.K., et al. 1990. J. Biol. Chem. 265, 17401.
      Product Information
      FormLiquid
      FormulationIn 100 mM NaCl, 50 mM sodium phosphate, 1 mM EDTA, pH 6.6.
      PreservativeNone
      Quality LevelMQ100
      Applications
      Application ReferencesParaffin Sections Coukos, G., et al. 1994. Am. J. Pathol. 144, 383. Daugherty, A., and Rateri, D.L. 1994. Arterioscler Thromb. 14, 2017. Rebeck, G.W., et al. 1993. Neuron 11, 575.
      Key Applications Frozen Sections
      Immunoblotting (Western Blotting)
      Paraffin Sections
      Application NotesFrozen Sections (1-5 µg/ml)
      Immunoblotting (1-5 µg/ml)
      Paraffin Sections (1-5 µg/ml, see application references)
      Application CommentsVariables associated with assay conditions will dictate the proper working dilution.
      Biological Information
      Immunogenpurified, human placenta LRP
      ImmunogenHuman
      Clone5A6
      HostMouse
      IsotypeIgG₂
      Species Reactivity
      • Human
      • Mouse
      • Rabbit
      Antibody TypeMonoclonal Antibody
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      438192-100UGCN 07790788050283

      Documentation

      Anti-LRP, Light Chain Mouse mAb (5A6) SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-LRP, Light Chain Mouse mAb (5A6) Certificates of Analysis

      TitleLot Number
      438192

      References

      Reference overview
      Mikhailenko, I., et al. 2001. J. Biol. Chem. 276, 39484.
      Rebeck, W.G., et al. 2001. Mol. Brain Res. 87, 238.
      Coukos, G., et al. 1994. Am. J. Pathol. 144, 383.
      Daugherty, A., and Rateri, D.L. 1994. Arterioscler Thromb. 14, 2017.
      Strickland, D.K., et al. 1990. J. Biol. Chem. 265, 17401.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision06-September-2008 JSW
      SynonymsAnti-Low Density Lipoprotein Receptor-Related Protein
      ApplicationFrozen Sections (1-5 µg/ml)
      Immunoblotting (1-5 µg/ml)
      Paraffin Sections (1-5 µg/ml, see application references)
      Application Data
      Detection of light chain LRP by immunoblotting. Samples: Soluble LRP at 500 ng (lane 1) and 50 ng (lane 2) with prestained standard (lane 3). Primary antibody: Anti-LRP, Light Chain Mouse mAb (5A6) (Cat. No. 438192) (1 µg/ml). Detection: chemiluminescence.
      DescriptionPurified mouse monoclonal antibody. Recognizes the ~85 kDa LRP light chain protein under non-reducing conditions.
      BackgroundLRP (Low Density Lipoprotein Receptor-Related Protein) contributes to the pathology of Alzheimer's disease by influencing both the production and clearance of the β-amyloid peptide.
      HostMouse
      Immunogen speciesHuman
      Immunogenpurified, human placenta LRP
      Clone5A6
      IsotypeIgG₂
      Specieshuman, mouse, rabbit
      FormLiquid
      FormulationIn 100 mM NaCl, 50 mM sodium phosphate, 1 mM EDTA, pH 6.6.
      Concentration Label Please refer to vial label for lot-specific concentration
      PreservativeNone
      CommentsVariables associated with assay conditions will dictate the proper working dilution.
      Storage Avoid freeze/thaw
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Standard Handling
      ReferencesMikhailenko, I., et al. 2001. J. Biol. Chem. 276, 39484.
      Rebeck, W.G., et al. 2001. Mol. Brain Res. 87, 238.
      Coukos, G., et al. 1994. Am. J. Pathol. 144, 383.
      Daugherty, A., and Rateri, D.L. 1994. Arterioscler Thromb. 14, 2017.
      Strickland, D.K., et al. 1990. J. Biol. Chem. 265, 17401.
      Application referencesParaffin Sections Coukos, G., et al. 1994. Am. J. Pathol. 144, 383. Daugherty, A., and Rateri, D.L. 1994. Arterioscler Thromb. 14, 2017. Rebeck, G.W., et al. 1993. Neuron 11, 575.