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ABS236 Anti-Cytochrome P450 (scc) Antibody, a.a. 509-526

This Cytochrome P450 (scc) antibody is validated for use in WB & IHC for the detection of the Cytochrome P450 (scc) protein.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Developmental Signaling Gene Symbol: Cyp11a1, Cyp11a, Cyp11a-1 UniProt Number: P14137
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ABS236
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      RWB, IH(P)RbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABS236
      ReplacesAB1294
      DescriptionAnti-Cytochrome P450 (scc) Antibody, a.a. 509-526
      Alternate Names
      • Cholesterol side-chain cleavage enzyme, mitochondrial
      • CYPXIA1
      • Cholesterol desmolase
      • Cytochrome P450 11A1
      • Cytochrome P450(scc)
      Background InformationAs a member of the cytochrome P450 family, Cytochrome P450 Side Chain Cleavage Enzyme (scc) catalyzes the side-chain cleavage reaction of cholesterol to pregnenolone during the first step of steroid biosynthesis. It is expressed in certain organs, such as ovaries, adrenal glands, and testis. Deficiency in CYP11A1 is commonly associated with adrenal insufficiency, and with variable degrees of disorder of sex development (DSD).
      References
      Product Information
      FormatAffinity Purified
      Control
      • Rat adrenal tissue lysate
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Cytochrome P450 (scc) antibody is validated for use in WB & IHC for the detection of the Cytochrome P450 (scc) protein.
      Key Applications
      • Western Blotting
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry Analysis: A 1:4,000-8,000 dilution from a representative lot detected Cytochrome P450 (scc) in rat adrenal gland and rat testis tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the C-terminus of rat Cytochrome P450 (scc), a.a. 509-526.
      EpitopeC-terminus
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody recognizes the C-terminus of Cytochrome P450 (scc), a.a. 509-526.
      Species Reactivity
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • Cyp11a1
      • Cyp11a
      • Cyp11a-1
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~52 kDa observed. On higher percentage gels and longer exposures, 8 kDa cleavage product can be detected.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in rat adrenal tissue lysate.

      Western Blot Analysis: 0.02 µg/mL of this antibody detected Cytochrome P450 (scc) in 10 µg of rat adrenal tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABS236 04053252847738

      Documentation

      Anti-Cytochrome P450 (scc) Antibody, a.a. 509-526 SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Cytochrome P450 (scc) Antibody, a.a. 509-526 Certificates of Analysis

      TitleLot Number
      Anti-Cytochrome P450 (scc), a.a. 509-526 - Q2115841 Q2115841
      Anti-Cytochrome P450 (scc), a.a. 509-526 - 2986142 2986142
      Anti-Cytochrome P450 (scc), a.a. 509-526 - 3267891 3267891
      Anti-Cytochrome P450 (scc), a.a. 509-526 - 3546847 3546847
      Anti-Cytochrome P450 (scc), a.a. 509-526 - 3944548 3944548
      Anti-Cytochrome P450 (scc), a.a. 509-526 -2503030 2503030
      Anti-Cytochrome P450 (scc), a.a. 509-526 -2683268 2683268

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies