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116801 Adenosine 3ʹ,5ʹ-cyclic Monophosphate, Sodium Salt - CAS 37839-81-9 - Calbiochem

A key regulator of many cellular reactions.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: A-3:5-MP, cAMP, Na

Primary Target: Protein kinase A
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116801
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
37839-81-9C₁₀H₁₁N₅O₆P · Na

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116801-100MGCN
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      		 Glass bottle 100 mg
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      116801-1GMCN
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          		 Plastic ampoule 1 gm
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          Description
          OverviewA key regulator of many cellular reactions. Released in response to hormonal stimulation. An activator of protein kinase A. Directly activates Epac, a Rap1 guanine-nucleotide exchange factor. Acts as a second messenger in signal transduction mechanisms. Promotes apoptosis in resting human B lymphocytes.
          Catalogue Number116801
          Brand Family Calbiochem®
          SynonymsA-3:5-MP, cAMP, Na
          References
          ReferencesKawasaki, H., et al. 1998. Science 282, 2275.
          de Rooij, J., et al. 1998. Nature 396, 474.
          Lomo, J., et al. 1995. J. Immunol. 154, 1634.
          Product Information
          CAS number37839-81-9
          ATP CompetitiveN
          FormWhite solid
          Hill FormulaC₁₀H₁₁N₅O₆P · Na
          Chemical formulaC₁₀H₁₁N₅O₆P · Na
          Hygroscopic Hygroscopic
          ReversibleN
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Primary TargetProtein kinase A
          Purity≥98% by HPLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSAU7357900
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          Catalogue Number GTIN
          116801-100MGCN 04055977208191
          116801-1GMCN 04055977208184

          Documentation

          Adenosine 3ʹ,5ʹ-cyclic Monophosphate, Sodium Salt - CAS 37839-81-9 - Calbiochem Certificates of Analysis

          TitleLot Number
          116801

          References

          Reference overview
          Kawasaki, H., et al. 1998. Science 282, 2275.
          de Rooij, J., et al. 1998. Nature 396, 474.
          Lomo, J., et al. 1995. J. Immunol. 154, 1634.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision07-April-2008 RFH
          SynonymsA-3:5-MP, cAMP, Na
          DescriptionA key regulator of many cellular reactions. Second messenger molecule released in response to hormonal stimulation. An activator of protein kinase A. Induces the guanine-nucleotide-exchange factor activity of GEFI, also known as Epac (exchange protein directly activated by cAMP), and GEFII towards Rap1 both in vitro and in vivo. Promotes apoptosis in resting human B lymphocytes.
          FormWhite solid
          CAS number37839-81-9
          RTECSAU7357900
          Chemical formulaC₁₀H₁₁N₅O₆P · Na
          Structure formulaStructure formula
          Purity≥98% by HPLC
          SolubilityH₂O (10 mg/ml)
          Storage -20°C
          Hygroscopic
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Toxicity Standard Handling
          Merck USA index14, 2708
          ReferencesKawasaki, H., et al. 1998. Science 282, 2275.
          de Rooij, J., et al. 1998. Nature 396, 474.
          Lomo, J., et al. 1995. J. Immunol. 154, 1634.