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100107 A23187, 4-Bromo- - CAS 76455-48-6 - Calbiochem

Brominated analog of the widely used cation ionophore A23187. Non-fluorescent and therefore suitable for use in the presence of fluorescent or metal-chelating probes.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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100107
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
76455-48-6C₂₉H₃₆BrN₃O₆

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100107-1MGCN
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      Description
      OverviewBrominated analog of the widely used cation ionophore A23187 (Cat. No. 100105). Non-fluorescent and therefore suitable for use in the presence of fluorescent or metal-chelating probes.
      Catalogue Number100107
      Brand Family Calbiochem®
      References
      ReferencesDeber, C.M., and Hsu, L.C. 1986. Biochem. Biophys. Res. Commun. 134, 731.
      Deber, C.M., et al. 1985. Anal. Biochem. 146, 349.
      Product Information
      CAS number76455-48-6
      ATP CompetitiveN
      FormYellow solid
      Hill FormulaC₂₉H₃₆BrN₃O₆
      Chemical formulaC₂₉H₃₆BrN₃O₆
      Hygroscopic Hygroscopic
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetCation ionophore
      Purity≥90% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 20/21/22-36/37/38

      Harmful by inhalation, in contact with skin and if swallowed.
      Irritating to eyes, respiratory system and skin.
      S PhraseS: 26-36/37/39

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing, gloves and eye/face protection.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      100107-1MGCN 04055977226270

      Documentation

      A23187, 4-Bromo- - CAS 76455-48-6 - Calbiochem Certificates of Analysis

      TitleLot Number
      100107

      References

      Reference overview
      Deber, C.M., and Hsu, L.C. 1986. Biochem. Biophys. Res. Commun. 134, 731.
      Deber, C.M., et al. 1985. Anal. Biochem. 146, 349.

      Citations

      Title
    • Norman J. Kennedy, et al. (2007) Requirement of JIP scaffold proteins for NMDA-mediated signal transduction. Genes and Development 21, 2336-2346.
      		•
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision02-December-2009 RFH
      DescriptionBrominated analog of the widely used cation ionophore A23187 (Cat. No. 100105). Non-fluorescent and therefore suitable for use in the presence of fluorescent or metal-chelating probes.
      FormYellow solid
      CAS number76455-48-6
      Chemical formulaC₂₉H₃₆BrN₃O₆
      Structure formulaStructure formula
      Purity≥90% by HPLC
      SolubilityDMSO (100 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
      Toxicity Harmful
      ReferencesDeber, C.M., and Hsu, L.C. 1986. Biochem. Biophys. Res. Commun. 134, 731.
      Deber, C.M., et al. 1985. Anal. Biochem. 146, 349.
      Citation
    • Norman J. Kennedy, et al. (2007) Requirement of JIP scaffold proteins for NMDA-mediated signal transduction. Genes and Development 21, 2336-2346.
      		•

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      Categories

      Life Science Research > Inhibitors and Biochemicals > Biochemicals > Ionophores