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107478 1,2-Propanediol

Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
57-55-6200-338-0C₃H₈O₂CH₃CH(OH)CH₂OH76.09 g/molPh Eur,BP,USP

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      Plastic bottle 2.5 l
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      Description
      Catalogue Number107478
      Synonyms1,2-Propylene glycol
      Description1,2-Propanediol
      References
      Product Information
      CAS number57-55-6
      EC number200-338-0
      GradePh Eur,BP,USP
      Hill FormulaC₃H₈O₂
      Chemical formulaCH₃CH(OH)CH₂OH
      Molar Mass76.09 g/mol
      HS Code2905 32 00
      Structure formula ImageStructure formula Image
      Quality LevelMQ500
      Applications
      Biological Information
      Physicochemical Information
      Boiling point188 °C (1013 hPa)
      Density1.036 g/cm3 (25 °C)
      Explosion limit2.4 - 17.4 %(V)
      Flash point99 °C
      Ignition temperature371 °C
      Melting Point-59 °C
      pH value6 - 8 (100 g/l, H₂O, 20 °C)
      Vapor pressure0.2 hPa (25 °C)
      Refractive Index1.43 (20 °C)
      Dimensions
      Materials Information
      Toxicological Information
      LD 50 oralLD50 Rat 19400 - 36000 mg/kg
      LD 50 dermalLD50 Rabbit 20800 mg/kg
      Safety Information according to GHS
      RTECSTY2000000
      Storage class10 - 13 Other liquids and solids
      WGKWGK 1 slightly hazardous to water
      Disposal3
      Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      StorageStore at +2°C to +30°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Assay (GC)≥ 99.5 %
      Identity (IR)conforms
      Identity C (USP) (GC)conforms
      Appearance of the substanceconforms
      Density (d 20 °C/20 °C)1.035 - 1.040
      Density (d 25 °C/25 °C)1.035 - 1.037
      Refractive index (n 20/D)1.431 - 1.433
      Acidityconforms
      Chloride (Cl)≤ 70 ppm
      Sulfate (SO₄)≤ 60 ppm
      Diethylene glycol (GC)≤ 0.10 %
      Ethylene glycol (GC)≤ 620 ppm
      Residual solvents (ICH Q3C)excluded by production process
      Oxidizing substancesconforms
      Reducing substancesconforms
      Sulfated ash≤ 0.007 %
      Water≤ 0.2
      Bacterial endotoxins≤ 2.5 I.U./ml
      Total aerobic microbial count (TAMC)≤ 10²
      Total combined yeasts/moulds count (TYMC)
      ≤ 10¹
      Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities).
      Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
      Conforms to Ph Eur, BP, USP.
      ≤ 10¹
      Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities).
      Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
      **The value of the additional identity test is transferred from the supplier CoA.
      Conforms to Ph Eur, BP, USP
      Global Trade Item Number
      Catalogue Number GTIN
      1.07478.2500 04022536091136

      Documentation

      Material Qualification Dossier

      TitleVersion
      8.0

      Quality Management Dossier (Open Access)

      Title

      Operational Excellence Dossier

      Title

      1,2-Propanediol SDS

      Title

      Safety Data Sheet (SDS) 

      1,2-Propanediol Certificates of Analysis

      Product Number PackagingSpecificationLot Number
      1.07478.2500 Plastic bottlePDF Specification Document

      Certificates

      Title