Acute Injury and Chronic Neurodegeneration
Fluoro-Ruby Reagent Neurons of the thalamic parafascicular nucleus seen following injection of Fluoro-Ruby Reagent into the striatum.
Fluoro-Ruby Reagent (Cat. No. AG335) Neurons of the thalamic parafascicular nucleus seen following injection of Fluoro-Ruby Reagent into the striatum.

A general feature of many neurological diseases, disorders, or injuries is the degeneration of proximal and/or distal neural processes. Key to understanding the degenerative progression is detecting and staining these dying neurons. EMD-Millipore has developed several methods for detecting neurodegeneration in blood/CSF samples and tissue sections. Several ELISA based assays are now available for neurodegenerative biomarkers, including phosphoNF-H, GFAP, and alpha synuculein. In addtion, Millipore’s non-antibody based tissue section stains for various stages of degenerating neurons are very robust regardless of specific insult or mechanism of cell death.