Millipore Sigma Vibrant Logo

108386 Tris(hydroxymethyl)aminomethane

(Trometamol) EMPROVE® EXPERT Ph Eur,BP,ChP,JPC,USP

Tris(hydroxymethyl)aminomethane MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Trometamol, Aminomethylidine trimethanol, 2-Amino-2-hydroxymethyl-1.3-propanediol, TRIS-buffer

CAS #: 77-86-1 EC Number: 201-064-4 Molar Mass: 121.14 g/mol Chemical Formula: H₂NC(CH₂OH)₃ Hill Formula: C₄H₁₁NO₃ Grade: Ph Eur,BP,ChP,JPC,USP
View Products on Sigmaaldrich.com
108386
View Pricing & Availability
Learn about the Emprove® Program

Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
77-86-1201-064-4C₄H₁₁NO₃H₂NC(CH₂OH)₃121.14 g/molPh Eur,BP,ChP,JPC,USP

Pricing & Availability

Catalogue Number AvailabilityPackaging Qty/Pack Price Quantity
1083861000
Retrieving availability...
—
Limited Availability Limited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      		 Plastic bottle 1 kg
      Retrieving price...
      Price could not be retrieved
      Minimum Quantity is a multiple of
      Maximum Quantity is
      Upon Order Completion More Information
      You Saved ()
       
      —
      Request Pricing
      		 —
      1083865000
      Retrieving availability...
      —
      Limited Availability Limited Availability
      In Stock 
      Discontinued
      Limited Quantities Available
      Availability to be confirmed
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service
          Contact Customer Service

          		 Plastic bottle 5 kg
          Retrieving price...
          Price could not be retrieved
          Minimum Quantity is a multiple of
          Maximum Quantity is
          Upon Order Completion More Information
          You Saved ()
           
          —
          Request Pricing
          		 —
          1083869025
          Retrieving availability...
          —
          Limited Availability Limited Availability
          In Stock 
          Discontinued
          Limited Quantities Available
          Availability to be confirmed
            Remaining : Will advise
              Remaining : Will advise
              Will advise
              Contact Customer Service
              Contact Customer Service

              		 25 kg
              Retrieving price...
              Price could not be retrieved
              Minimum Quantity is a multiple of
              Maximum Quantity is
              Upon Order Completion More Information
              You Saved ()
               
              —
              Request Pricing
              		 —
              Description
              Catalogue Number108386
              SynonymsTrometamol, Aminomethylidine trimethanol, 2-Amino-2-hydroxymethyl-1.3-propanediol, TRIS-buffer
              DescriptionTris(hydroxymethyl)aminomethane
              References
              Product Information
              CAS number77-86-1
              EC number201-064-4
              GradePh Eur,BP,ChP,JPC,USP
              Hill FormulaC₄H₁₁NO₃
              Chemical formulaH₂NC(CH₂OH)₃
              Molar Mass121.14 g/mol
              HS Code2922 19 99
              Structure formula ImageStructure formula Image
              Quality LevelMQ500
              Applications
              Biological Information
              Physicochemical Information
              Boiling point219 - 220 °C (13.3 hPa)
              Density1.32 g/cm3 (20 °C)
              Melting Point169 °C
              pH value10.2 - 10.6 (6 g/l, H₂O, 20 °C)
              Vapor pressure<0.1 hPa (20 °C)
              Bulk density840 kg/m3
              Solubility678 g/l
              Dimensions
              Materials Information
              Toxicological Information
              LD 50 oralLD50 Rat > 5000 mg/kg
              LD 50 dermalLD50 Rat > 5000 mg/kg
              Safety Information according to GHS
              RTECSTY2900000
              Storage class10 - 13 Other liquids and solids
              WGKWGK 1 slightly hazardous to water
              Disposal3
              Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
              Safety Information
              Product Usage Statements
              Storage and Shipping Information
              StorageNoTempLimit
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications
              Global Trade Item Number
              Catalogue Number GTIN
              1083861000 04022536103846
              1083865000 04022536775487
              1083869025 04022536103853

              Documentation

              Material Qualification Dossier

              TitleVersion
              6.0

              Quality Management Dossier (Open Access)

              Title

              Operational Excellence Dossier

              Title

              Tris(hydroxymethyl)aminomethane SDS

              Title

              Safety Data Sheet (SDS) 

              Tris(hydroxymethyl)aminomethane Certificates of Analysis

              Product Number PackagingSpecificationLot Number
              1083861000 Plastic bottlePDF Specification Document
              1083865000 Plastic bottlePDF Specification Document
              1083869025 PDF Specification Document

              Certificates

              Title

              Related Products & Applications

              Related Products By: Application Facete

              Antibody Purification

              Related Products By: Brand Facete

              EMPROVE®

              Categories

              Biopharmaceutical Manufacturing > Downstream Processing > Chromatography > Process Chemicals > Buffers
              Small Molecule Pharmaceuticals > Formulation > Semisolid Dosage Form > Acidulants and pH Adjustments
              Biopharmaceutical Manufacturing > Formulation > Liquid Dosage > pH Adjustments and Isotonizers
              Small Molecule Pharmaceuticals > Formulation > Liquid Dosage Form > pH Adjustments and Isotonizers