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109253 Papanicolaou's solution 1a Harris' hematoxylin solution

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109253
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1092530500
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      1092531000
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          1092531022
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              1092532500
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                  GT11092531002
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                      1 l
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                      GT11092531022
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                          1 PC
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                          Description
                          Catalogue Number109253
                          SynonymsHematoxylin solution acc. to Harris, Colour solution acc. to Papanicolaou, Harris' Hematoxylin solution
                          DescriptionPapanicolaou’s solution 1a Harris hematoxylin solution
                          OverviewPapanicolaou’s solution 1a Harris hematoxylin solution - for cytology, is a ready-to-use solution used for human-medical cell diagnosis and serve the purpose of the cytological investigation of sample material of human origin, for example, gynecological and clinico-cytological specimen materials. Papanicolaou’s technique is the most used staining procedure for cytological specimen is and is intended for the the staining of exfoliative cells in cytological specimens. In the first step, the cell nuclei are stained either progressively or regressively with a hematoxylin solution, (Hematoxylin solution modified acc.to Gill II, (Cat.no. 105175), Papanicolaou’s solution 1a Harris hematoxylin solution, (Cat.no. 109253) or Papanicolaou’s solution 1b Hematoxylin solution S, (Cat.no. 109254)). Nuclei are stained blue to dark violet. In the progressive hematoxylin staining method, staining is carried out to the endpoint, after which the slide is blued in tapwater. With the regressive method the material is over-stained and the excess of staining solution is removed by acid rinsing steps, followed by the bluing step. The structures of nuclei are more differentiated and better visible by the regressive method. The second staining step is cytoplasmic staining by (Papanicolaou’s solution 2b Orange II solution, (Cat. no. 1106887) or Papanicolaou’s solution 2a Orange G solution (OG6), (Cat. no. 106888)), especially for demonstration of mature and keratinized cells. The target structures are stained orange in different intensities. In the third staining step is used the so-called polychrome solution, a mixture of eosin, light green SF and Bismarck brown, Papanicolaou’s solution 3a polychromatic solution EA 31, (Cat.no 109271), Papanicolaou’s solution 3b polychromatic solution EA 50, (Cat.no. 109272), Papanicolaou’s solution 3c polychromatic solution EA 65,(Cat.no. 109270), or Papanicolaou’s solution 3d polychromatic solution EA 65, (Cat.no.109269). The polychrome solution is used for demonstration of differentiation of squamous cells. Both Papanicolaou’s solution 1a Harris hematoxylin solution(Cat.no. 109253) and Papanicolaou’s solution 1b Hematoxylin solution S (Cat.no. 109254) give a blue to dark violet staining result with clinical specimen material.
                          A 500 ml bottle of either solution is sufficient for 1500 -2500 stainings. It is registered as IVD and CE certified product and can be used for clinical diagnostics. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.
                          References
                          Product Information
                          HS Code3212 90 00
                          Quality LevelMQ400
                          Applications
                          Applicationfor cytology
                          Biological Information
                          Physicochemical Information
                          Boiling point100 °C (1013 hPa)
                          Density1.04 g/cm3 (20 °C)
                          pH value2.5 - 3.0 (H₂O, 20 °C)
                          Dimensions
                          Materials Information
                          Toxicological Information
                          Safety Information according to GHS
                          Hazard Pictogram(s) Hazard Pictogram(s)
                          Hazard Statement(s)H318: Causes serious eye damage.
                          EUH210: Safety data sheet available on request.
                          Precautionary Statement(s)P280: Wear eye protection/ face protection.
                          P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
                          Signal WordDanger
                          Storage class10 - 13 Other liquids and solids
                          WGKWGK 1 slightly hazardous to water
                          Disposal28
                          Aqueous solutions: Container D.
                          Safety Information
                          Product Usage Statements
                          Storage and Shipping Information
                          StorageStore at +15°C to +25°C.
                          Packaging Information
                          Transport Information
                          Supplemental Information
                          Specifications
                          Suitability for microscopy (Vaginal smear)passes test
                          Nucleiblue to dark violet
                          Cyanophilic Cytoplasm (basophilic)blue-green
                          Eosinophilic Cytoplasm (acidophilic)pink
                          Global Trade Item Number
                          Catalogue Number GTIN
                          1092530500 04022536112466
                          1092531000 04022536676661
                          1092531022 04022536707433
                          1092532500 04022536112480
                          GT11092531002 04061839134799
                          GT11092531022 04061839134805

                          Documentation

                          Papanicolaou's solution 1a Harris' hematoxylin solution SDS

                          Title

                          Safety Data Sheet (SDS) 

                          Papanicolaou's solution 1a Harris' hematoxylin solution Certificates of Analysis

                          Product Number PackagingSpecificationLot Number
                          1092530500 Plastic bottlePDF Specification Document
                          1092531000 Plastic bottlePDF Specification Document
                          1092531022 Plastic bottlePDF Specification Document
                          1092532500 Plastic bottlePDF Specification Document
                          GT11092531002 PDF Specification Document
                          GT11092531022 PDF Specification Document

                          User Guides

                          Title
                          109253 Solución de Papanicolaou 1a solución de hematoxilina según Harris para citología
                          109253 Solución de Papanicolaou 1a solución de hematoxilina según Harris para citología (versión de Cuba)
                          User Guide (IFU) - 109253

                          Related Products & Applications

                          Accessories (Primary)

                          Catalogue Number Description  
                          106887 Papanicolaou’s solution 2b Orange II solution Show Pricing & Availability
                          106888 Papanicolaou's solution 2a Orange G solution (OG 6) Show Pricing & Availability
                          109254 Papanicolaou's solution 1b Hematoxylin solution S Show Pricing & Availability
                          109269 Papanicolaou's solution 3d polychromatic solution EA 65 Show Pricing & Availability
                          109271 Papanicolaou's solution 3a polychromatic solution EA 31 Show Pricing & Availability
                          109272 Papanicolaou's solution 3b polychromatic solution EA 50 Show Pricing & Availability
                          115938 Hematoxylin monohydrate (C.I.75290) Show Pricing & Availability
                          109270 Papanicolaou's solution 3c Polychromatic solution EA 65 Show Pricing & Availability

                          Accessories (Secondary)

                          Catalogue Number Description  
                          104302 Hematoxylin cryst. (C.I. 75290) Show Pricing & Availability
                          105175 Hematoxylin solution modified acc. to Gill II Show Pricing & Availability
                          106887 Papanicolaou’s solution 2b Orange II solution Show Pricing & Availability
                          106888 Papanicolaou's solution 2a Orange G solution (OG 6) Show Pricing & Availability
                          109254 Papanicolaou's solution 1b Hematoxylin solution S Show Pricing & Availability
                          109269 Papanicolaou's solution 3d polychromatic solution EA 65 Show Pricing & Availability
                          109271 Papanicolaou's solution 3a polychromatic solution EA 31 Show Pricing & Availability
                          109272 Papanicolaou's solution 3b polychromatic solution EA 50 Show Pricing & Availability
                          109270 Papanicolaou's solution 3c Polychromatic solution EA 65 Show Pricing & Availability

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                          Categories

                          IVD/OEM Materials & Reagents > Microscopy > Cytology > Cytological Staining Reagents