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100202 N,N-Dimethylformamide

Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaChemical FormulaMolar Mass
68-12-2200-679-5C₃H₇NOHCON(CH₃)₂73.09 g/mol

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      1002022500
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          Description
          Catalogue Number100202
          SynonymsDMF, N,N-Dimethylmethanamide, Formic acid dimethylamide
          DescriptionN,N-Dimethylformamide
          OverviewSupraSolv® solvents for headspace gas chromatography are developed particularly for the analysis of residual solvents in drug substances, excipients and drug products according to ICH, Ph Eur and USP - SupraSolv® headspace solvents are tested for all residual solvents defined by the ICH.
          References
          Product Information
          CAS number68-12-2
          EC index number616-001-00-X
          EC number200-679-5
          Hill FormulaC₃H₇NO
          Chemical formulaHCON(CH₃)₂
          Molar Mass73.09 g/mol
          HS Code2924 19 00
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          ApplicationN,N-Dimethylformamide for headspace gas chromatography SupraSolv®. CAS 68-12-2, EC Number 200-679-5, chemical formula HCON(CH₃)₂.
          Biological Information
          Physicochemical Information
          Boiling point153 °C (1013 hPa)
          Density0.944 g/cm3 (25 °C)
          Explosion limit2.2 - 16 %(V)
          Flash point57.5 °C
          Ignition temperature410 °C
          Melting Point-61 °C (External MSDS)
          pH value7 (200 g/l, H₂O, 20 °C)
          Vapor pressure3.77 hPa (20 °C)
          Solubility1000 g/l soluble
          Dimensions
          Materials Information
          Toxicological Information
          LD 50 oralLD50 Rat 3010 mg/kg
          LD 50 dermalLD50 Rabbit 1500 mg/kg
          Safety Information according to GHS
          Hazard Pictogram(s) Hazard Pictogram(s)
          Hazard Pictogram(s)
          Hazard Pictogram(s)
          Hazard Statement(s)H226: Flammable liquid and vapour.
          H312 + H332: Harmful in contact with skin or if inhaled.
          H319: Causes serious eye irritation.
          H360D: May damage the unborn child.
          Precautionary Statement(s)P210: Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
          P280: Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection.
          P303 + P361 + P353: IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water.
          P304 + P340 + P312: IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell.
          P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
          P308 + P313: IF exposed or concerned: Get medical advice/ attention.
          Signal WordDanger
          RTECSLQ2100000
          Storage class3 Flammable liquids
          WGKWGK 2 obviously hazardous to water
          Disposal3
          Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
          Safety Information
          Categories of dangertoxic for reproduction, harmful, irritant
          Product Usage Statements
          Storage and Shipping Information
          StorageStore at +2°C to +30°C.
          Packaging Information
          Transport Information
          Declaration (railroad and road) ADR, RIDUN 2265 , 3, III
          Declaration (transport by air) IATA-DGRUN 2265 , 3, III
          Declaration (transport by sea) IMDG-CodeUN 2265 , 3, III
          Supplemental Information
          Specifications
          Purity (GC)≥ 99.8 %
          Identity (IR)conforms
          Evaporation residue≤ 3.0 mg/l
          Water≤ 0.05 %
          Color≤ 10 Hazen
          GC/HS (Every residual solvent of class 1 acc. ICH)≤ 1 µg/g
          GC/HS (Every residual solvent of class 2 acc. ICH)≤ 10 µg/g
          GC/HS (Every residual solvent of class 3 acc. ICH)≤ 50 µg/g
          Suitable as solvent for the analysis of residual solvents of ICH classes 1,2 and 3 according to Ph Eur und USP.
          Formic acid and acetic acid are not detected.
          Global Trade Item Number
          Catalogue Number GTIN
          1002021000 04027269198053
          1002022500 04027269198060

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          Categories

          Analytics and Sample Preparation > Analytical Chromatography > Gas Chromatography GC > Solvents for Headspace Gas Chromatography, SupraSolv®
          Reagents, Chemicals and Labware > Solvents > Solvents for Instrumental Organic Analysis > Solvents for Headspace Gas Chromatography, SupraSolv®