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341006 EDAC, Hydrochloride

EDAC HCl is a water-soluble derivative of carbodiimide useful for conjugating haptens to proteins and polypeptides. Used to modify NMDA receptors and as a condensing agent in peptide synthesis.

EDAC, Hydrochloride MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: EDCI, 1-Ethyl-3-(3ʹ-dimethylaminopropyl)carbodiimide, HCl

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341006
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Overview

Replacement Information

Key Spec Table

CAS #Purity
25952-53-8≥98% by Titration

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      		 Plastic ampoule 5 gm
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      Description
      OverviewWater-soluble carbodiimide derivative. Used to modify NMDA receptors. Also useful for conjugating haptens to proteins or polypeptides.
      Molar absorptivity (~212 nm; 50 mM phosphate buffer, pH 8):≥6800 M-1cm-1.
      Catalogue Number341006
      Brand Family Calbiochem®
      SynonymsEDCI, 1-Ethyl-3-(3ʹ-dimethylaminopropyl)carbodiimide, HCl
      References
      ReferencesChazot, P.L., et al. 1993. Biochem. Pharmacol. 45, 605.
      Richardson, A., et al. 1992. Biochem. Pharmacol. 43, 1415.
      Taniuchi, M., et al. 1986. Proc. Natl. Acad. Sci. USA 83, 1950.
      Chase, J.W., et al. 1983. Proc. Natl. Acad. Sci. USA 80, 5480.
      Williams, A., et al. 1981. J. Am. Chem. Soc. 103, 7090.
      Yamada, H., et al. 1981. Biochemistry 20, 4836.
      Thomas, J.O., et al. 1978. J. Mol. Biol. 123, 149.
      Ozawa, H. 1970. Biochemistry 9, 2158.
      Kopple, K.D., et al. 1962. J. Am. Chem. Soc. 84, 4457.
      Product Information
      CAS number25952-53-8
      FormWhite solid
      Hill FormulaC₈H₁₇N₃ · HCl
      Chemical formulaC₈H₁₇N₃ · HCl
      Hygroscopic Hygroscopic
      Structure formula ImageStructure formula Image
      Quality LevelMQ200
      Applications
      Biological Information
      Purity≥98% by Titration
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSFF2200000
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage -20°C
      Protect from Moisture Protect from moisture
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsUnstable in solution. Reconstitute just prior to use.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      341006-5GM 04055977215403

      Documentation

      EDAC, Hydrochloride SDS

      Title

      Safety Data Sheet (SDS) 

      EDAC, Hydrochloride Certificates of Analysis

      TitleLot Number
      341006

      References

      Reference overview
      Chazot, P.L., et al. 1993. Biochem. Pharmacol. 45, 605.
      Richardson, A., et al. 1992. Biochem. Pharmacol. 43, 1415.
      Taniuchi, M., et al. 1986. Proc. Natl. Acad. Sci. USA 83, 1950.
      Chase, J.W., et al. 1983. Proc. Natl. Acad. Sci. USA 80, 5480.
      Williams, A., et al. 1981. J. Am. Chem. Soc. 103, 7090.
      Yamada, H., et al. 1981. Biochemistry 20, 4836.
      Thomas, J.O., et al. 1978. J. Mol. Biol. 123, 149.
      Ozawa, H. 1970. Biochemistry 9, 2158.
      Kopple, K.D., et al. 1962. J. Am. Chem. Soc. 84, 4457.

      Brochure

      Title
      Excitotoxic Glutamate Analogs Technical Bulletin
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision17-October-2017 JSW
      SynonymsEDCI, 1-Ethyl-3-(3ʹ-dimethylaminopropyl)carbodiimide, HCl
      DescriptionWater-soluble derivative of carbodiimide useful for conjugating haptens to proteins and polypeptides. Used to modify NMDA receptors and as a condensing agent in peptide synthesis. The major advantage of EDAC coupling is the easy removal of excess reagent and the corresponding urea by washing with dilute acid or water. Carbodiimides catalyze the formation of amide bonds, carboxylic acids, and amines by activating the carboxylate to form an O-acylurea. This intermediate can be attacked by an amine directly to form an amide. EDAC is released as a soluble urea derivative.
      FormWhite solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number25952-53-8
      RTECSFF2200000
      Chemical formulaC₈H₁₇N₃ · HCl
      Structure formulaStructure formula
      Purity≥98% by Titration
      SolubilityH₂O (2-5 mg/ml) or Aqueous buffers (2-5 mg/ml). Avoid amine containing buffers.
      Storage Protect from moisture
      -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsUnstable in solution. Reconstitute just prior to use.
      Toxicity Irritant
      ReferencesChazot, P.L., et al. 1993. Biochem. Pharmacol. 45, 605.
      Richardson, A., et al. 1992. Biochem. Pharmacol. 43, 1415.
      Taniuchi, M., et al. 1986. Proc. Natl. Acad. Sci. USA 83, 1950.
      Chase, J.W., et al. 1983. Proc. Natl. Acad. Sci. USA 80, 5480.
      Williams, A., et al. 1981. J. Am. Chem. Soc. 103, 7090.
      Yamada, H., et al. 1981. Biochemistry 20, 4836.
      Thomas, J.O., et al. 1978. J. Mol. Biol. 123, 149.
      Ozawa, H. 1970. Biochemistry 9, 2158.
      Kopple, K.D., et al. 1962. J. Am. Chem. Soc. 84, 4457.