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475956 c-Myc Inhibitor - CAS 403811-55-2 - Calbiochem

The c-Myc Inhibitor, also referenced under CAS 403811-55-2, controls the biological activity of c-Myc.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 10058-F4, (Z,E)-5-(4-Ethylbenzylidine)-2-thioxothiazolidin-4-one

Primary Target: c-Myc
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
403811-55-2C₁₂H₁₁NOS₂

Products

Catalogue NumberPackaging Qty/Pack
475956-10MG Plastic ampoule 10 mg
Description
OverviewA cell-permeable thiazolidinone compound that specifically inhibits the c-Myc-Max interaction, thereby preventing the transactivation of c-Myc target gene expression. Shown to inhibit tumor cell growth in a c-Myc-dependent manner both in vitro and in vivo (64 μM using c-Myc transfected Rat1a fibroblasts).
Catalogue Number475956
Brand Family Calbiochem®
Synonyms10058-F4, (Z,E)-5-(4-Ethylbenzylidine)-2-thioxothiazolidin-4-one
References
ReferencesYin, X., et al. 2003. Oncogene 22, 6151.
Product Information
CAS number403811-55-2
ATP CompetitiveN
DeclarationSold under license of U.S. Patent 7,026,343.
FormYellow solid
Hill FormulaC₁₂H₁₁NOS₂
Chemical formulaC₁₂H₁₁NOS₂
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Targetc-Myc
Purity≥95% by HPLC (sum of two isomers)
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Carcinogenic / Teratogenic
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
475956-10MG 04055977184303

Documentation

c-Myc Inhibitor - CAS 403811-55-2 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

c-Myc Inhibitor - CAS 403811-55-2 - Calbiochem Certificates of Analysis

TitleLot Number
475956

References

Reference overview
Yin, X., et al. 2003. Oncogene 22, 6151.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision13-April-2011 RFH
Synonyms10058-F4, (Z,E)-5-(4-Ethylbenzylidine)-2-thioxothiazolidin-4-one
DescriptionA cell-permeable, thiazolidinone compound that specifically inhibits c-Myc-Max interaction, thereby preventing the transactivation of c-Myc targeted gene expression. Shown to inhibit tumor cell growth in a c-Myc-dependent manner both in vitro and in vivo (Effective concentration: 64 µM using c-Myc-transfected Rat1a fibroblasts).
FormYellow solid
Intert gas (Yes/No) Packaged under inert gas
CAS number403811-55-2
Chemical formulaC₁₂H₁₁NOS₂
Structure formulaStructure formula
Purity≥95% by HPLC (sum of two isomers)
SolubilityDMSO (200 mg/ml)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Carcinogenic / Teratogenic
ReferencesYin, X., et al. 2003. Oncogene 22, 6151.