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48-602MAG
Buffer Detection Kit for Magnetic Beads
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567540
Sigma-AldrichSodium Orthovanadate - CAS 13721-39-6 - Calbiochem
A broad spectrum potent inhibitor of protein tyrosine phosphatases.
More>>A broad spectrum potent inhibitor of protein tyrosine phosphatases. Less<<
MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
A broad spectrum potent inhibitor of protein tyrosine phosphatases. Also known to inhibit Na+,K+-ATPase, acid and alkaline phosphatases, phosphofructokinase, and adenylate kinase. Also inhibits the ATPase activity of the reconstituted binding protein-dependent ATP-Binding Cassette (ABC) transporter for maltose (MalFGK2) of Salmonella typhimurium in the micromolar range. Can be converted to pervanadate by hydrogen peroxide.
Catalogue Number
567540
Brand Family
Calbiochem®
Synonyms
PTP Inhibitor X
References
References
Huyer, G., et al. 1997. J. Biol. Chem. 272, 843. Hunke, S., et al. 1995. Biochem. Biophys. Res. Commun.216, 589. Levchuck, S.G., et al. 1994. Pediatric Res.37, 382A. Fohr, K.J., et al. 1989. Biochem. J.262, 83. Swarup, G., et al. 1982. Biochem. Biophys. Res. Commun.107, 1104. Seargeant, L.E. and Stinson, R.A. 1979. Biochem. J.181, 247.
Hendrik Ungefroren, et al. (2001) FAP-1 in pancreatic cancer cells: functional and mechanistic studies on its inhibitory role in CD95-mediated apoptosis. Journal of Cell Science114, 2735-2746.
Data Sheet
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
10-October-2018 JSW
Synonyms
PTP Inhibitor X
Description
A broad spectrum potent inhibitor of protein tyrosine phosphatases. Also known to inhibit Na+/K+ ATPase, acid and alkaline phosphatases, phosphofructokinase, and adenylate kinase. Most recently shown to inhibit ATPase activity of the reconstituted binding protein-dependent ATP-Binding Cassette (ABC) transporter for maltose (MalFGK2) of Salmonella typhimurium in the micromolar range. Can be converted to pervanadate by hydrogen peroxide.
Form
White to off-white solid
CAS number
13721-39-6
RTECS
YW1120000
Chemical formula
Na₃VO₄
Solubility
H₂O (10 mg/ml)
Storage
+15°C to +30°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity
Harmful
References
Huyer, G., et al. 1997. J. Biol. Chem. 272, 843. Hunke, S., et al. 1995. Biochem. Biophys. Res. Commun.216, 589. Levchuck, S.G., et al. 1994. Pediatric Res.37, 382A. Fohr, K.J., et al. 1989. Biochem. J.262, 83. Swarup, G., et al. 1982. Biochem. Biophys. Res. Commun.107, 1104. Seargeant, L.E. and Stinson, R.A. 1979. Biochem. J.181, 247.
Hendrik Ungefroren, et al. (2001) FAP-1 in pancreatic cancer cells: functional and mechanistic studies on its inhibitory role in CD95-mediated apoptosis. Journal of Cell Science114, 2735-2746.
