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557450 Ruthenium Red - CAS 11103-72-3 - Calbiochem

A blocker of transmembrane Ca2+ fluxes (IC₅₀ = 7 µM) that attenuates capsaicin-induced cation channel opening.

Ruthenium Red - CAS 11103-72-3 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Ammoniated Ruthenium Oxychloride, RR

Primary Target: Blocker of transmembrane Ca2+ fluxes
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
12790-48-6[(NH₃)₅RuORu(NH₃)₄ORu(NH₃)₅]Cl₆

Products

Catalogue NumberPackaging Qty/Pack
557450-250MG Glass bottle 250 mg
Description
OverviewA blocker of transmembrane Ca2+ fluxes (IC50 = 7 µM) that attenuates capsaicin-induced cation channel opening. Inhibits Ca2+-induced Ca2+ release from ryanodine-sensitive intracellular Ca2+ stores. Inhibits K+-stimulated catecholamine secretion (IC50 = 6 µM).
Catalogue Number557450
Brand Family Calbiochem®
SynonymsAmmoniated Ruthenium Oxychloride, RR
References
ReferencesMerck Index 13, 8379.
Phillippe, M. and Basa, A. 1996. Biochem. Biophys. Res. Commun. 221, 656.
Buratti, R., et al. 1995. Biochem. Biophys. Res. Commun. 213, 1082.
Hamilton, M.G. and Lundy, P.M. 1995. J. Pharmacol. Exp. Ther. 273, 940.
Gomis, A., et al. 1994. Biochem. Pharmacol. 47, 225.
Stjame, P., et al. 1994. Acta Otolaryngol. 114, 651.
Ma, J. 1993. J. Gen. Physiol. 102, 1031.
Product Information
CAS number12790-48-6
ATP CompetitiveN
FormRed-black solid
Hill Formula[(NH₃)₅RuORu(NH₃)₄ORu(NH₃)₅]Cl₆
Chemical formula[(NH₃)₅RuORu(NH₃)₄ORu(NH₃)₅]Cl₆
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Primary TargetBlocker of transmembrane Ca2+ fluxes
Primary Target IC<sub>50</sub>7 µM in blocking transmembrane Ca2+ fluxes; 6 µM inhibiting K+-stimulated catecholamine secretion
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 22

Harmful if swallowed.
S PhraseS: 22

Do not breathe dust.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful
Storage +15°C to +30°C
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
557450-250MG 04055977268096

Documentation

Ruthenium Red - CAS 11103-72-3 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Ruthenium Red - CAS 11103-72-3 - Calbiochem Certificates of Analysis

TitleLot Number
557450

References

Reference overview
Merck Index 13, 8379.
Phillippe, M. and Basa, A. 1996. Biochem. Biophys. Res. Commun. 221, 656.
Buratti, R., et al. 1995. Biochem. Biophys. Res. Commun. 213, 1082.
Hamilton, M.G. and Lundy, P.M. 1995. J. Pharmacol. Exp. Ther. 273, 940.
Gomis, A., et al. 1994. Biochem. Pharmacol. 47, 225.
Stjame, P., et al. 1994. Acta Otolaryngol. 114, 651.
Ma, J. 1993. J. Gen. Physiol. 102, 1031.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision10-May-2024 JSW
SynonymsAmmoniated Ruthenium Oxychloride, RR
DescriptionA blocker of transmembrane Ca2+ fluxes (IC50 = 7 µM) that attenuates capsaicin-induced cation channel opening. Inhibits Ca2+-induced Ca2+ release from ryanodine-sensitive intracellular Ca2+ stores. Inhibits K+-stimulated catecholamine secretion (IC50 = 6 µM).
FormRed-black solid
CAS number12790-48-6
Chemical formula[(NH₃)₅RuORu(NH₃)₄ORu(NH₃)₅]Cl₆
SolubilityH₂O or ammonia
Storage Protect from moisture
+15°C to +30°C
Do Not Freeze Ok to freeze
Toxicity Harmful
Merck USA index14, 8300
ReferencesMerck Index 13, 8379.
Phillippe, M. and Basa, A. 1996. Biochem. Biophys. Res. Commun. 221, 656.
Buratti, R., et al. 1995. Biochem. Biophys. Res. Commun. 213, 1082.
Hamilton, M.G. and Lundy, P.M. 1995. J. Pharmacol. Exp. Ther. 273, 940.
Gomis, A., et al. 1994. Biochem. Pharmacol. 47, 225.
Stjame, P., et al. 1994. Acta Otolaryngol. 114, 651.
Ma, J. 1993. J. Gen. Physiol. 102, 1031.