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Design and price your MILLIPLEX® MAP kits.
Our broad portfolio consists of multiplex panels that allow you to choose, within the panel, analytes that best meet your needs. On a separate tab you can choose the premixed cytokine format or a single plex kit.
Choose fixed kits that allow you to explore entire pathways or processes. Or design your own kits by choosing single plex MAPmates™, following the provided guidelines.
The following MAPmates™ should not be plexed together:
-MAPmates™ that require a different assay buffer
-Phospho-specific and total MAPmate™ pairs, e.g. total GSK3β and GSK3β (Ser 9)
-PanTyr and site-specific MAPmates™, e.g. Phospho-EGF Receptor and phospho-STAT1 (Tyr701)
-More than 1 phospho-MAPmate™ for a single target (Akt, STAT3)
-GAPDH and β-Tubulin cannot be plexed with kits or MAPmates™ containing panTyr
.
| Catalogue Number | Ordering Description | Qty/Pack | List |
To begin designing your MILLIPLEX® MAP kit select a species, a panel type or kit of interest.
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Panel Type |
Selected Kit |
Sample Type |
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| Select A Sample Type | For some panels, sample type will determine which analytes can be plexed together. |
Design your own kit or select from our premixed and single plex panels.
| Catalogue Number | Ordering Description | Qty/Pack | List |
| Species |
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| Panel Type | |
| Selected Kit | |
| Qty | Catalogue Number | Ordering Description | Qty/Pack | List Price |
| 96-Well Plate |
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| Qty | Catalogue Number | Ordering Description | Qty/Pack | List Price |
| 48-602MAG | Buffer Detection Kit for Magnetic Beads | 1 Kit |
You can now customize another kit, choose a premixed kit, check out or close the ordering tool.
| Life Science Research > Antibodies and Assays > Primary Antibodies |
Akt/PKB is a Ser/Thr kinase and a major known effecter of the PI3 Kinase pathway. It is involved in multiple signaling pathways that relate to many biological processes including metabolism, apoptosis, cell cycle control, angiogenesis, differentiation, and cell growth and proliferation. In mammals, three isoforms of Akt (Akt1/PKCα, Akt2/PKBβ, and Akt3/PKBγ) exists. They exhibit a high degree of homology, but differ slightly in the localization of their regulatory phosphorylation sites. Akt1 is the predominant isoform that is in most tissues and is thought to have a dominant role in growth, survival, embryonic development, and adipocyte differentiation. Akt2 is correlated with the regulation of glucose homeostasis and is the predominant isoform expressed in insulin-responsive tissues. Akt3 is abundant in brain tissue. Each Akt isoform is composed of three functionally distinct regions: an N-terminal Pleckstrin Homology (PH) domain that provides a lipid-binding module, a central catalytic domain containing Thr308, and a C-terminal hydrophobic motif containing Ser473. The activation of AKT is dependent on a dual regulatory mechanism that requires both its translocation to the plasma membrane and dual phosphorylation on Thr308 and Ser473 by PDK1 and the TORC2 complex, respectively. EMD Millipore’s phospho-Akt antibodies are based on the expertise of Upstate & Chemicon. Our phospho-Akt antibodies have been well validated and published. See the ordering tab for a comprehensive list of our phospho-Akt products and direct links to their technical pages for data, references and related products.