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505226 Pancuronium Dibromide - CAS 15500-66-0 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 1,1ʹ-(3α,17β-Dihydroxy-2α,5β-androstan-2-β,16β-ylene) bis[1-methylpiperidinium] diacetate dibromide, Nicotinic Acetylchorine Receptor Antagonist, Pancuronium Dibromide, nAChR Antagonist, Pancuronium Dibromide

Primary Target: nAChR
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
15500-66-0C₃₅H₆₀N₂O₄•Br₂

Products

Catalogue NumberPackaging Qty/Pack
5052260001 Glass bottle 10 mg
Description
OverviewA highly potent competitive antagonist selective for nAChRs (IC50 = 5.5 nM). A very potent non-depolarizing skeletal muscle relaxant but no sedative or analgesic effects.
Catalogue Number505226
Brand Family Calbiochem®
Synonyms1,1ʹ-(3α,17β-Dihydroxy-2α,5β-androstan-2-β,16β-ylene) bis[1-methylpiperidinium] diacetate dibromide, Nicotinic Acetylchorine Receptor Antagonist, Pancuronium Dibromide, nAChR Antagonist, Pancuronium Dibromide
References
ReferencesLowenick et al., 2001. Eur. J. Pharmacol. 413, 31.
Melnikov, L., et al., 1999. Gen Pharmacol. 33, 313.
Maestrone, E., et al., 1994. Br. J. Pharmacol. 111, 283.
Fryer, D., et al., 1987. Naunyn Schmiedebergs Arch. Pharmacol. 335, 367.
Product Information
CAS number15500-66-0
FormOff-white solid
Hill FormulaC₃₅H₆₀N₂O₄•Br₂
Chemical formulaC₃₅H₆₀N₂O₄•Br₂
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetnAChR
Primary Target IC<sub>50</sub>5.5nM
Purity≥98% by NMR
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 25-62-63

Toxic if swallowed.
Possible risk of impaired fertility.
Possible risk of harm to the unborn child.
S PhraseS: 36/37/39-45-46

Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
If swallowed, seek medical advice immediately and show this container or label.
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Toxic
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
5052260001 04055977263497

Documentation

Pancuronium Dibromide - CAS 15500-66-0 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

References

Reference overview
Lowenick et al., 2001. Eur. J. Pharmacol. 413, 31.
Melnikov, L., et al., 1999. Gen Pharmacol. 33, 313.
Maestrone, E., et al., 1994. Br. J. Pharmacol. 111, 283.
Fryer, D., et al., 1987. Naunyn Schmiedebergs Arch. Pharmacol. 335, 367.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision26-July-2013 JSW
Synonyms1,1ʹ-(3α,17β-Dihydroxy-2α,5β-androstan-2-β,16β-ylene) bis[1-methylpiperidinium] diacetate dibromide, Nicotinic Acetylchorine Receptor Antagonist, Pancuronium Dibromide, nAChR Antagonist, Pancuronium Dibromide
DescriptionA highly potent competitive antagonist selective for nAChRs (IC50 = 5.5 nM). A very potent non-depolarizing skeletal muscle relaxant but no sedative or analgesic effects.
FormOff-white solid
CAS number15500-66-0
Chemical formulaC₃₅H₆₀N₂O₄•Br₂
Structure formulaStructure formula
Purity≥98% by NMR
SolubilityH₂O (100 mM)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Toxic
ReferencesLowenick et al., 2001. Eur. J. Pharmacol. 413, 31.
Melnikov, L., et al., 1999. Gen Pharmacol. 33, 313.
Maestrone, E., et al., 1994. Br. J. Pharmacol. 111, 283.
Fryer, D., et al., 1987. Naunyn Schmiedebergs Arch. Pharmacol. 335, 367.