Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

101728 OSTEOSOFT®

mild decalcifier-solution for histology

OSTEOSOFT® MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
101728
Purchase on Sigma-Aldrich

Overview

Replacement Information

Products

Catalogue NumberPackaging Qty/Pack
1017281000 Plastic bottle 1 l
1017289010 Titripac PE/Alu 10 l
Description
Catalogue Number101728
DescriptionOSTEOSOFT®
OverviewThis ready-to-use product, OSTEOSOFT® - mild decalcifier-solution for histology, has been specifically developed for human cell diagnostics in humans and is used for the demineralization and decalcification of bones, punched bone-marrow specimens, and other hard tissue of human origin.
Decalcification is necessary for optical microscopic examinations of hard tissue in routine histological procedures. For the decalcification of sensitive, calcium-containing tissues, such as iliac crest biopsies, OSTEOSOFT® can be used. Its formulation is based on EDTA. Its pendant, OSTEOMOLL®(Cat. no. 101736), can be used for the decalcification of hard tissue such as teeth and bone as its formulation is based on formaldehyde and acetic acid. The amount of OSTEOSOFT®needed is dependent upon on the size, type and thickness of the material. Both solutions are color-coded, to distinguish them from each other, fixatives and solvents used in the histological laboratory. OSTEOSOFT® is color-coded yellow, OSTEOMOLL® is color-coded blue. Whereby OSTEOSOFT® preserves the antigen structures in the tissue, thus, an IHC analysis can be performed, OSTEOMOLL® will be used for tissues that are not destined for antibody analysis.
Both decalcifiers can be used for clinical diagnostic purposes and in laboratory accreditation processes as they are certified and registered as IVD and CE product. OSTEOSOFT® is used only once and fresh solution must be used for each tissue. The quantity of OSTEOSOFT® required is dependent on the size, type, and density of the respective material. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.
References
Product Information
HS Code3824 99 92
Quality LevelMQ400
Applications
Applicationmild decalcifier-solution for histology
Biological Information
Physicochemical Information
Density1.10 g/cm3 (20 °C)
pH value7.0 - 7.3 (H₂O, 20 °C)
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Hazard Pictogram(s) Hazard Pictogram(s)
Hazard Pictogram(s)
Hazard Statement(s)H318: Causes serious eye damage.
H373: May cause damage to organs through prolonged or repeated exposure if inhaled.
Precautionary Statement(s)P260: Do not breathe dust/ fume/ gas/ mist/ vapours/ spray.
P280: Wear eye protection/ face protection.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P314: Get medical advice/ attention if you feel unwell.
P501: Dispose of contents/ container to an approved waste disposal plant.
Signal WordDanger
Storage class10 - 13 Other liquids and solids
WGKWGK 2 obviously hazardous to water
Disposal3
Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at +15°C to +25°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
1017281000 04022536929019
1017289010 04027269312374