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14-909M MELK Protein, active, 250 µg

Active, recombinant human MELK (amino acids 1 -340), containing an N-terminal GST tag, for use in Kinase Assays.

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14-909M
250 µg  Also available in 0 μg size (cat#14-909) and in bulk (cat# 14-909-K).
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Overview

Replacement Information

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This enzyme is part of KinaseProfiler™, a custom inhibitor selectivity discovery service.
Description
Catalogue Number14-909M
Brand Family Upstate
Trade Name
  • Upstate
DescriptionMELK Protein, active, 250 µg
OverviewRecombinant human MELK (amino acids 1 - 340), containing an N-terminal GST tag
Alternate Names
  • HPK38
  • PK38
  • pEg3 kinase
Background InformationMaternal embryonic leucine zipper kinase (MELK) is a conserved serine/threonine kinase involved in a variety of cellular functions, including proliferation, differentiation and apoptosis. Its levels are elevated in a number of tumour types and it may be a prognosis marker for some cancers.
References
Product Information
Quality LevelMQ300
Applications
ApplicationActive, recombinant human MELK (amino acids 1 -340), containing an N-terminal GST tag, for use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
SourceRecombinant protein of the human MELK gene expressed by baculovirus in insect cells
Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
Gene Symbol
  • MELK
Purification MethodPurified using glutathione-agarose
Target Sub-FamilyCAMK
UniProt Number
Molecular Weight66 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated by phosphorylation of KKLNRTLSFAEPG
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C
Packaging Information
Material Size250 µg
Material PackageAlso available in 0 μg size (cat#14-909) and in bulk (cat# 14-909-K).
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
14-909M 04053252468384

Documentation