Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

407653 Interleukin-6 Receptor, Soluble, Human, Recombinant, S. frugiperda

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: rhIL-6 sR

View Products on Sigmaaldrich.com
407653
Purchase on Sigma-Aldrich

Overview

Replacement Information

Products

Catalogue NumberPackaging Qty/Pack
407653-25UG Plastic ampoule 25 μg
Description
OverviewRecombinant, human soluble interleukin-6 receptor expressed in S. frugiperda insect cells. Soluble form of the IL-6 receptor that binds IL-6 and mediates IL-6 signaling through interaction with gp130. Elevated serum levels of soluble IL-6 receptors have been shown to be associated with a number of pathological states including multiple myelomas, adult T cell leukemia, interstitial lung infection, and HIV infection.
Catalogue Number407653
Brand Family Calbiochem®
SynonymsrhIL-6 sR
References
ReferencesSchobitz, B., et al. 1995. FASEB J. 9, 659.
Yokoyama, A., et al. 1995. Clin. Exp. Immunol. 100, 325.
Suzuki, H., et al. 1993. Eur. J. Immunol. 23, 1078.
Lust, J.A., et al. 1992. Cytokine 4, 96.
Sugita, T., et al. 1990. J. Exp. Med. 171, 2001.
Yamasaki, K., et al. 1988. Science 241, 825.
Product Information
FormLyophilized
FormulationLyophilized from sterile-filtered PBS, 50 µg BSA/µg IL-6 receptor.
Quality LevelMQ100
Applications
Biological Information
Biological activityED₅₀= ≥5 ng/ml as measured by its ability to enhance IL-6-induced growth inhibition of mouse M1 myeloid leukemic cells
Purity≥97% by SDS-PAGE
Physicochemical Information
ContaminantsEndotoxin: ≤1 EU/µg
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage ≤ -70°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 month at 4°C. Avoid freeze/thaw cycles of solutions.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
407653-25UG 04055977211412

Documentation

Interleukin-6 Receptor, Soluble, Human, Recombinant, S. frugiperda SDS

Title

Safety Data Sheet (SDS) 

Interleukin-6 Receptor, Soluble, Human, Recombinant, S. frugiperda Certificates of Analysis

TitleLot Number
407653

References

Reference overview
Schobitz, B., et al. 1995. FASEB J. 9, 659.
Yokoyama, A., et al. 1995. Clin. Exp. Immunol. 100, 325.
Suzuki, H., et al. 1993. Eur. J. Immunol. 23, 1078.
Lust, J.A., et al. 1992. Cytokine 4, 96.
Sugita, T., et al. 1990. J. Exp. Med. 171, 2001.
Yamasaki, K., et al. 1988. Science 241, 825.

Brochure

Title
Stem Cell Resource Brochure GBP
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision07-May-2010 JSW
SynonymsrhIL-6 sR
DescriptionRecombinant, human soluble interleukin-6 receptor expressed in S. frugiperda insect cells. Soluble form of the IL-6 receptor that binds IL-6 and mediates IL-6 signaling through interaction with gp 130. Elevated serum levels of soluble IL-6 receptors have been shown to be associated with a number of pathological states, including multiple myelomas, adult T cell leukemia, interstitial lung infection, and HIV infection.
FormLyophilized
FormulationLyophilized from sterile-filtered PBS, 50 µg BSA/µg IL-6 receptor.
Purity≥97% by SDS-PAGE
ContaminantsEndotoxin: ≤1 EU/µg
Biological activityED₅₀= ≥5 ng/ml as measured by its ability to enhance IL-6-induced growth inhibition of mouse M1 myeloid leukemic cells
SolubilityReconstitute to a concentration ≥100 µg/ml with sterile PBS containing at least 0.1% HSA or BSA.
Storage ≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 month at 4°C. Avoid freeze/thaw cycles of solutions.
Toxicity Standard Handling
ReferencesSchobitz, B., et al. 1995. FASEB J. 9, 659.
Yokoyama, A., et al. 1995. Clin. Exp. Immunol. 100, 325.
Suzuki, H., et al. 1993. Eur. J. Immunol. 23, 1078.
Lust, J.A., et al. 1992. Cytokine 4, 96.
Sugita, T., et al. 1990. J. Exp. Med. 171, 2001.
Yamasaki, K., et al. 1988. Science 241, 825.