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540223 InSolution™ Purmorphamine - Calbiochem

InSolution™ Purmorphamine, CAS 483367-10-8, is a provided as a 50 mM solution in DMSO. Induces osteoblast differentiation of multipotent mesenchymal progenitor cells C3H10T1/2 & lineage-committed preosteoblasts MC3T3-E1.

InSolution™ Purmorphamine - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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540223
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₃₁H₃₂N₆O₂

Products

Catalogue NumberPackaging Qty/Pack
540223-5MG Plastic ampoule 5 mg
Description
Catalogue Number540223
Brand Family Calbiochem®
References
ReferencesWu, X., et al. 2004. Chem. Biol. 11, 1229.
Wu, X., et al. 2002. J. Am. Chem. Soc. 124, 14520.
Product Information
FormLiquid
FormulationA 50 mM (5 mg/192 µl) solution of Purmorphamine (Cat. No. 540220) in DMSO.
Hill FormulaC₃₁H₃₂N₆O₂
Chemical formulaC₃₁H₃₂N₆O₂
Hygroscopic Hygroscopic
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
ApplicationInSolution™ Purmorphamine, CAS 483367-10-8, is a provided as a 50 mM solution in DMSO. Induces osteoblast differentiation of multipotent mesenchymal progenitor cells C3H10T1/2 & lineage-committed preosteoblasts MC3T3-E1.
Biological Information
Purity≥98% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 36/38

Irritating to eyes and skin.
S PhraseS: 26-36-45

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped with Blue Ice or with Dry Ice
Toxicity Irritant
Storage -20°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
540223-5MG 04055977268782

Documentation

InSolution™ Purmorphamine - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

InSolution™ Purmorphamine - Calbiochem Certificates of Analysis

TitleLot Number
540223

References

Reference overview
Wu, X., et al. 2004. Chem. Biol. 11, 1229.
Wu, X., et al. 2002. J. Am. Chem. Soc. 124, 14520.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision26-August-2008 JSW
DescriptionA cell-permeable purine compound that induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells (EC50 = 1 µM) and in MC3T3-E1 lineage-committed preosteoblasts. Also shown to induce transdifferentiation in pre-adipocytes and myoblasts. Its effects are reported to be synergistic with bone morphogenetic protein-4 (BMP-4). Reported to induce osteogenesis by activation of the Hedgehog signaling pathway.
FormLiquid
FormulationA 50 mM (5 mg/192 µl) solution of Purmorphamine (Cat. No. 540220) in DMSO.
Intert gas (Yes/No) Packaged under inert gas
Chemical formulaC₃₁H₃₂N₆O₂
Structure formulaStructure formula
Purity≥98% by HPLC
Storage Protect from light
-20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Toxicity Irritant
ReferencesWu, X., et al. 2004. Chem. Biol. 11, 1229.
Wu, X., et al. 2002. J. Am. Chem. Soc. 124, 14520.