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GF443 HumanKine® TPO, Human Recombinant Xeno-Free

HumanKine® TPO, Human Recombinant Xeno-Free MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
UniProt Number: P40225
GF443
10 µg  
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Overview

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Key Spec Table

SourcePurity
HumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free.Product is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 95% pure by SDS-PAGE.
Description
Catalogue NumberGF443
Trade Name
  • HumanKine®
DescriptionHumanKine® TPO, Human Recombinant Xeno-Free
Alternate Names
  • Thrombopoeitin
  • THPO
Background InformationActivins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release. Activin proteins have a wide range of biological activities, including mesoderm induction, neural cell differentiation, bone remodeling, hematopoiesis and roles in reproductive physiology. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, follistatin. Humankine Activin A is disulfide linked homodimer with an apparent molecular mass of 25 kDa. This cytokine is produced in a serum-free, chemically defined media.
Product Information
Formulation
PresentationProduct is presented in PBS and filtered through a 0.2 micron filter before lyophilization.
Quality LevelMQ300
Biological Information
PurityProduct is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 95% pure by SDS-PAGE.
SourceHumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free.
UniProt Number
Product Usage Statements
Quality AssuranceBioactivity assay: Determined by the dose-dependent stimulation of the proliferation of human TF-1 cells (human erythroleukemic
indicator cell line). ED50 is typically 0.5-5 ng/ml.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore at -20°C for up to 4 months from date of receipt. Further dilutions should be made into appropriate buffer or medium to which protein has been added.
Packaging Information
Material Size10 µg
Global Trade Item Number
Catalogue Number GTIN
GF443 04053252906107