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14-1067 Human Recombinant MeCP2 (methyl-CpG-binding protein 2)

Human recombinant N-terminal His-tagged MeCP2 expressed in SF9 insect cells & purified by Fast Protein Liquid Chromatography (FPLC) & demonstrated to bind methylated DNA

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: DNA-binding Proteins
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14-1067
10 µg  
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Overview

Replacement Information
Description
Catalogue Number14-1067
DescriptionHuman Recombinant MeCP2 (methyl-CpG-binding protein 2)
OverviewHuman recombinant N-terminal His-tagged MeCP2 expressed in SF9 insect cells and purified by Fast Protein Liquid Chromatography (FPLC).
Background InformationMeCP2 (methyl-CpG-binding protein 2) binds methylated CpG sequences in double-stranded DNA resulting in the suppression of transcription. This protein is likely to be involved in the repression of multiple genes. Consistent with this role, mutations of MeCP2 are linked to Rett syndrome, a progressive neurological disorder that is one of the most common causes of mental retardation in females.
References
Product Information
PresentationIn a buffer containing 20 mM Tris-Cl pH 7.6, 1 mM EDTA, 0.15 M NaCl, 10% glycerol, 0.5 mM PMSF and 1 mM DTT.
Quality LevelMQ100
Applications
ApplicationHuman recombinant N-terminal His-tagged MeCP2 expressed in SF9 insect cells & purified by Fast Protein Liquid Chromatography (FPLC) & demonstrated to bind methylated DNA
Key Applications
  • DNA-binding Proteins
Biological Information
Concentration0.5 µg/µL
PurityGreater than 95% purity by SDS PAGE
Molecular Weight50.2 kDa including histidine tag
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable at -80ºC for 6 months from date of receipt.
Packaging Information
Material Size10 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
14-1067 04053252957437

Documentation

Human Recombinant MeCP2 (methyl-CpG-binding protein 2) SDS

Title

Safety Data Sheet (SDS) 

Human Recombinant MeCP2 (methyl-CpG-binding protein 2) Certificates of Analysis

TitleLot Number
Human Recombinant MeCP2 - QVP1312092 QVP1312092
Human Recombinant MeCP2 - VP1908120 VP1908120
Human Recombinant MeCP2 - VP2001102 VP2001102
Human Recombinant MeCP2 - VP2008120 VP2008120
Human Recombinant MeCP2 - VP2106240 VP2106240
Human Recombinant MeCP2 - VP22010500 VP22010500
Human Recombinant MeCP2 - VP2205230 VP2205230
Human Recombinant MeCP2 - VP2304100 VP2304100
Human Recombinant MeCP2 - VP2401080 VP2401080
Human Recombinant MeCP2 - VP2407100 VP2407100
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