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371780 GP Antagonist-2A - Calbiochem

Overview

Key Spec Table

Empirical Formula
C₇₉H₁₀₅N₂₁O₁₃S

Products

Catalogue NumberPackaging Qty/Pack
371780-1MG Plastic ampoule 1 mg
Description
OverviewA peptide that selectively inhibits the activation of Gq by M1-muscarinic cholinergic receptors. Also inhibits activation by cholecystokinin receptor in pancreatic acini at 10 µM. Blocks angiotensin II-stimulated sis-inducing factor and STAT3 tyrosine phosphorylation.
Catalogue Number371780
Brand Family Calbiochem®
SynonymsRPKPQQDWFDWDWM
References
ReferencesHunt, R.A., et al. 1999. Hypertension 34, 603.
Tsunoda Y., et al. 1995. Biochem. Biophys. Res. Commun. 211, 648.
Mukai, H., et al. 1992. J. Biol. Chem. 267, 16237.
Product Information
ATP CompetitiveN
FormLyophilized solid
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₇₉H₁₀₅N₂₁O₁₃S
Chemical formulaC₇₉H₁₀₅N₂₁O₁₃S
ReversibleN
Quality LevelMQ100
Biological Information
Primary TargetInhibits the activation of Gq by M1-muscarinic cholinergic receptors
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Peptide SequenceH-Arg-Pro-Lys-Pro-Gln-Gln-D-Trp-Phe-D-Trp-D-Trp-Met-NH₂
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Global Trade Item Number
Catalogue Number GTIN
371780-1MG 04055977213409