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FC014 Fibronectin, Bovine

Fibronectin, Bovine MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: Cell Culture
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FC014
500 µg  
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Overview

Replacement Information

Key Spec Table

Key Applications
CULT
Description
Catalogue NumberFC014
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionFibronectin, Bovine
OverviewBovine fibronectin was purified from bovine plasma over a gelatin agarose column. A single band at 220kDa (reduced) is identified, corresponding to intact fibronectin under reduced conditions.
References
Product Information
PresentationLiquid in a solution of 2M Urea in 0.05 M Tris pH 7.0.
Quality LevelMQ100
Applications
Key Applications
  • Cell Culture
Application NotesELISA, Ouchterlony and immunoblotting.
Biological Information
Concentration1.0 mg/mL
PurityAffinity purified to approximately 95%, as determined by SDS-PAGE.
SourceBovine plasma
Entrez Gene SummaryThis gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined.
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P02751 # Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Interaction with TNR mediates inhibition of cell adhesion and neurite outgrowth (By similarity).
SIZE: 2386 amino acids; 262607 Da
SUBUNIT: Mostly heterodimers or multimers of alternatively spliced variants, connected by 2 disulfide bonds near the carboxyl ends; to a lesser extent homodimers. Interacts with FBLN1, AMBP, TNR, LGALS3BP and COL13A1.
SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix.
TISSUE SPECIFICITY: Plasma FN (soluble dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. Ugl-Y1, Ugl-Y2 and Ugl-Y3 are found in urine.DEVELOPMENTAL STAGE: Ugl-Y1, Ugl-Y2 and Ugl-Y3 are present in the urine from 0 to 17 years of age.
PTM: Sulfated.
SIMILARITY: SwissProt: P02751 ## Contains 12 fibronectin type-I domains. & Contains 2 fibronectin type-II domains. & Contains 16 fibronectin type-III domains.
Stem Cell Type
  • Mouse Embryonic Stem Cells
  • Mesenchymal Stem Cells
  • Neural Stem Cells
  • Hematopoietic Stem Cells
  • Epithelial Cells
  • Pancreatic Stem Cells
  • Induced Pluripotent Stem Cells
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsAliquot and store up to 12 months at -20°C. For short term (1-2 weeks) use, storage at 2-8°C is acceptable. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size500 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
FC014 04053252269929

Documentation

Fibronectin, Bovine SDS

Title

Safety Data Sheet (SDS) 

Fibronectin, Bovine Certificates of Analysis

TitleLot Number
BOVINE FIBRONECTIN 3137670
BOVINE FIBRONECTIN 3148497
BOVINE FIBRONECTIN 2474922
BOVINE FIBRONECTIN - 2060959 2060959
BOVINE FIBRONECTIN - 2301407 2301407
BOVINE FIBRONECTIN - 2851773 2851773
BOVINE FIBRONECTIN - 3277150 3277150
BOVINE FIBRONECTIN - 3386889 3386889
BOVINE FIBRONECTIN - 3388666 3388666
BOVINE FIBRONECTIN - 3499849 3499849
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References

Reference overviewPub Med ID
Comparative studies on amniotic fluid and plasma fibronectins
Ruoslahti E. et al.
Biochem. J, 193:295-299 (1981)  1981

7305927 7305927

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