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14-672M EphA7 Protein, active, 250 µg

14-672M
250 µg  Also available in 10 μg size (cat#14-672) and in bulk (cat#14-672-K).
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Catalogue Number14-672M
Brand Family Upstate
Trade Name
  • Upstate
DescriptionEphA7 Protein, active, 250 µg
OverviewN-terminal 6His-tagged, recombinant human EphA7, amino acids 613-909.
References
Product Information
Quality LevelMQ300
Applications
ApplicationActive, N-terminal 6His-tagged, recombinant human EphA7, amino acids 613-909. For use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
SourceHuman EphA7 613-909, expressed by baculovirus in Sf21 cells.
Entrez Gene Number
Entrez Gene SummaryThis gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
Gene Symbol
  • EPHA7
  • EphA7
  • EHK3
  • Hek11
  • OTTHUMP00000040586
  • HEK11
Protein TargetEphA7
Purification MethodNi2+/NTA-agarose
Target Sub-FamilyTK
UniProt Number
UniProt SummaryFUNCTION: SwissProt: Q15375 # Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A2, -A3, -A4 and -A5.
SIZE: 998 amino acids; 112097 Da
SUBUNIT: Interacts with PRKCABP and GRIP1 (By similarity).
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
TISSUE SPECIFICITY: Widely expressed.
SIMILARITY: SwissProt: Q15375 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. & Contains 2 fibronectin type-III domains. & Contains 1 protein kinase domain. & Contains 1 SAM (sterile alpha motif) domain.
Molecular Weight38kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated by phosphorylation of PDKtide.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C from date of shipment
Packaging Information
Material Size250 µg
Material PackageAlso available in 10 μg size (cat#14-672) and in bulk (cat#14-672-K).
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
14-672M 04053252924682

Documentation

Related Products & Applications

Alternative Packsize

Catalogue Number Description
14-672 EphA7 Protein, active, 10 µg

Product Families

Categories

Life Science Research > Proteins and Enzymes > Purified Kinases
Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases