Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

14-639M EphA5 Protein, active, 250 µg

Active, N-terminal His6-tagged human EphA5, expressed by baculovirus in Sf21 cells, for use in Kinase Assays.

View Products on Sigmaaldrich.com
14-639M
250 µg  Also available in 10 μg size (cat#14-639) and in bulk (cat#14-639-K).
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Catalogue Number14-639M
Brand Family Upstate
Trade Name
  • Upstate
DescriptionEphA5 Protein, active, 250 µg
OverviewN-terminal His6-tagged human EphA5, expressed by baculovirus in Sf21 cells
References
Product Information
Quality LevelMQ300
Applications
ApplicationActive, N-terminal His6-tagged human EphA5, expressed by baculovirus in Sf21 cells, for use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
Sourcerecombinant human EphA5, amino acids 655-956
Entrez Gene Number
Entrez Gene SummaryThis gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
Gene Symbol
  • EPHA5
  • EphA5
  • EHK1
  • TYRO4
  • HEK7
  • CEK7
  • Hek7
Protein TargetEphA5
Purification MethodNi2+/NTA-agarose
Target Sub-FamilyTK
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P54756 # Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A2, -A3, -A4 and -A5.
SIZE: 1037 amino acids; 114784 Da
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
TISSUE SPECIFICITY: Almost exclusively expressed in the nervous system.
SIMILARITY: SwissProt: P54756 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. & Contains 2 fibronectin type-III domains. & Contains 1 protein kinase domain. & Contains 1 SAM (sterile alpha motif) domain.
Molecular Weight37.9kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated by phosphorylation of Poly (Glu4-Tyr) (4:1) substrate
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C
Packaging Information
Material Size250 µg
Material PackageAlso available in 10 μg size (cat#14-639) and in bulk (cat#14-639-K).
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
14-639M 04053252924484

Documentation

Related Products & Applications

Alternative Packsize

Catalogue Number Description
14-639 EphA5 Protein, active, 10 µg

Product Families

Kinase & Phosphatase Products

Millipore offers a large portfolio of Kinases, Phophatases, Substrates, Inhibitors, Kits, reagents & tools for Signaling research. See below for a list of these products, in multiple pack sizes.
Learn More >>

Categories

Life Science Research > Proteins and Enzymes > Purified Kinases
Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases