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233501 Coagulation Factor XIII, Human Plasma

Coagulation Factor XIII, Human Plasma, CAS 9013-56-3, is a native tetrameric form composed of two identical α- and two β-subunits. Thrombin converts the α2β2 tetramer to a modified α2ʹβ2 tetramer.

Coagulation Factor XIII, Human Plasma MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Fibrin-stabilizing Factor

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233501
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Overview

Replacement Information

Products

Catalogue NumberPackaging Qty/Pack
233501-100UG Plastic ampoule 100 μg
Description
OverviewNative coagulation factor XIII from human plasma. Plasma Factor XIII is a tetramer (α2β2) composed of two identical α-subunits and two identical β-subunits. After thrombin cleavage converts the α2β2 tetramer to a modified α2′β2 tetramer, Ca2+ promotes both the dissociation of the β2 dimer and the activation of the α2′ dimer to its catalytically active form. This activated Factor XIII (Factor XIIIa) strengthens the fibrin clot by catalyzing the formation of glutamyl-lysine bonds between fibrin monomers.
Catalogue Number233501
Brand Family Calbiochem®
SynonymsFibrin-stabilizing Factor
References
Product Information
CAS number9013-56-3
Unit of DefinitionClotting activity is determined by comparison to a standard curve produced using normal pooled human plasma. One unit is defined as the activity in 1 ml of normal, pooled plasma.
FormLiquid
FormulationIn 500 µM EDTA, 50% glycerol.
Quality LevelMQ100
Applications
Biological Information
Purity≥95% by SDS-PAGE
SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Specific Activity≥40 units/mg protein (clotting assay)
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
233501-100UG 04055977217872

Documentation

Coagulation Factor XIII, Human Plasma SDS

Title

Safety Data Sheet (SDS) 

Coagulation Factor XIII, Human Plasma Certificates of Analysis

TitleLot Number
233501
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision29-April-2008 RFH
SynonymsFibrin-stabilizing Factor
DescriptionNative coagulation factor XIII from human plasma. Plasma Factor XIII is a tetramer (α2β2) composed of two identical α-subunits and two identical β-subunits. After thrombin cleavage converts the α2β2 tetramer to a modified α2'β2 tetramer, Ca2+ promotes both the dissociation of β2 dimer and the activation of the α2' dimer to its catalytically active form. This activated Factor XIII (Factor XIIIa) strengthens the fibrin clot by catalyzing the formation of glutamyl-lysine bonds between fibrin monomers.
FormLiquid
FormulationIn 500 µM EDTA, 50% glycerol.
Concentration Label Please refer to vial label for lot-specific concentration
SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
CAS number9013-56-3
Purity≥95% by SDS-PAGE
Specific activity≥40 units/mg protein (clotting assay)
Unit definitionClotting activity is determined by comparison to a standard curve produced using normal pooled human plasma. One unit is defined as the activity in 1 ml of normal, pooled plasma.
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Toxicity Standard Handling
Merck USA index14, 3926