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208694 Calmodulin, Bovine Brain, High Purity

Calmodulin is a ubiquitous Ca2+-binding protein that serves as a physiological effector of a wide range of biological processes. Purified from bovine brain.

Calmodulin, Bovine Brain, High Purity MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: CaM, Ca2+/Calmodulin

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Overview

Replacement Information

Products

Catalogue NumberPackaging Qty/Pack
208694-1MG Plastic ampoule 1 mg
208694-5MG Plastic ampoule 5 mg
Description
OverviewA ubiquitous Ca2+-binding protein that serves as a physiological effector of a wide range of biological processes. Calmodulin highly purified from bovine brain.
Note: this product cannot be used for animal treatment, in vivo research, or any contact procedure with livestock.
Catalogue Number208694
Brand Family Calbiochem®
SynonymsCaM, Ca2+/Calmodulin
References
ReferencesBagchi, I.C., et al. 1992. J. Biol. Chem. 267, 3024.
O'Neil, K.T., and DeGrado, W.F. 1990. Trends Pharmacol. Sci. 15, 59.
Harrison, J.K., et al. 1988. J. Neurochem. 51, 345.
Gopalakrishna, R., and Anderson, W.B. 1983. J. Biol. Chem. 258, 2405.
Gopalakrishna, R., and Anderson, W.B. 1982. Biochem. Biophys. Res. Commun. 104, 830.
Sharma, B.K., et al. 1979. Adv. Cyclic Nucleotide Res. 10, 187.
Product Information
CAS number73298-54-1
Unit of DefinitionOne unit is defined as the amount of calmodulin that gives rise to 50% of the maximal enzyme activation of a standard level of activator-deficient calcineurin.
FormLyophilized
FormulationLyophilized from 30 mM HEPES, 1 mM CaCl₂, 0.1 mM DTT, pH 7.4.
Sold on the basis of peptide contentY
Quality LevelMQ200
Applications
Biological Information
Purity≥95% by SDS-PAGE
Specific Activity≥250,000 units/mg protein
Physicochemical Information
Peptide ContentY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C or -70°C). Aqueous stock solutions are stable for up to 2 months at -20°C or for up to 4 months at -70°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
208694-1MG 04055977203325
208694-5MG 04055977203332

Documentation

Calmodulin, Bovine Brain, High Purity SDS

Title

Safety Data Sheet (SDS) 

Calmodulin, Bovine Brain, High Purity Certificates of Analysis

TitleLot Number
208694

References

Reference overview
Bagchi, I.C., et al. 1992. J. Biol. Chem. 267, 3024.
O'Neil, K.T., and DeGrado, W.F. 1990. Trends Pharmacol. Sci. 15, 59.
Harrison, J.K., et al. 1988. J. Neurochem. 51, 345.
Gopalakrishna, R., and Anderson, W.B. 1983. J. Biol. Chem. 258, 2405.
Gopalakrishna, R., and Anderson, W.B. 1982. Biochem. Biophys. Res. Commun. 104, 830.
Sharma, B.K., et al. 1979. Adv. Cyclic Nucleotide Res. 10, 187.

Citations

Title
  • Xinchun Shen, et al. (2005) Scanning the human proteome for calmodulin-binding proteins. Proceedings of the National Academy of Sciences (USA) 102, 5969-5974.
    		•
    Data Sheet

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision26-February-2014 JSW
    SynonymsCaM, Ca2+/Calmodulin
    DescriptionA ubiquitous Ca2+-binding protein distributed in eukaryotic cells that serves as a major physiological effector for a wide range of cellular responses. The Ca2+-calmodulin complex is involved in the maintenance of intracellular Ca2+ homeostasis, as well as in the regulation of the intracellular concentration of other second messengers, such as cyclic AMP and inositol trisphosphate. Calmodulin highly purified from bovine brain.

    Note: This product is not to be used for animal treatment, in vivo research or in any other contact procedure with livestock.
    FormLyophilized
    FormulationLyophilized from 30 mM HEPES, 1 mM CaCl₂, 0.1 mM DTT, pH 7.4.
    CAS number73298-54-1
    Purity≥95% by SDS-PAGE
    Specific activity≥250,000 units/mg protein
    Unit definitionOne unit is defined as the amount of calmodulin that gives rise to 50% of the maximal enzyme activation of a standard level of activator-deficient calcineurin.
    SolubilityAqueous buffers or H₂O. Please refer to the vial label for lot-specific reconstitution volume.
    Storage -20°C
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C or -70°C). Aqueous stock solutions are stable for up to 2 months at -20°C or for up to 4 months at -70°C.
    Toxicity Standard Handling
    Merck USA index14, 1719
    ReferencesBagchi, I.C., et al. 1992. J. Biol. Chem. 267, 3024.
    O'Neil, K.T., and DeGrado, W.F. 1990. Trends Pharmacol. Sci. 15, 59.
    Harrison, J.K., et al. 1988. J. Neurochem. 51, 345.
    Gopalakrishna, R., and Anderson, W.B. 1983. J. Biol. Chem. 258, 2405.
    Gopalakrishna, R., and Anderson, W.B. 1982. Biochem. Biophys. Res. Commun. 104, 830.
    Sharma, B.K., et al. 1979. Adv. Cyclic Nucleotide Res. 10, 187.
    Citation
  • Xinchun Shen, et al. (2005) Scanning the human proteome for calmodulin-binding proteins. Proceedings of the National Academy of Sciences (USA) 102, 5969-5974.
    		•