Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

MABT1498-100UL Anti-ZDHHC13 Antibody, clone 26D1

Anti-ZDHHC13, clone 26D1, Cat. No. MABT1498, is a mouse monoclonal antibody that detects Palmitoyltransferase ZDHHC13 and has been tested for use in Western Blotting.

Anti-ZDHHC13 Antibody, clone 26D1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Gene Symbol: ZDHHC13, HIP14L, HIP3RP UniProt Number: Q8IUH4-2
View Products on Sigmaaldrich.com
MABT1498-100UL
100 µL  
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABT1498-100UL
DescriptionAnti-ZDHHC13 Antibody, clone 26D1
Alternate Names
  • Palmitoyltransferase ZDHHC13
  • EC: 2.3.1.22
  • Huntingtin-interacting protein 14-related protein
  • HIP14-related protein
  • Huntingtin-interacting protein HIP3RP
  • Putative MAPK-activating protein PM03
  • Putative NF-kappa-B-activating protein 209
  • Zinc finger DHHC domain-containing protein 13
  • DHHC-13
Background InformationPalmitoyltransferase ZDHHC13 (UniProt: Q8IUH4; also known as EC: 2.3.1.22, Huntingtin-interacting protein 14-related protein, HIP14-related protein, Huntingtin-interacting protein HIP3RP, Putative MAPK-activating protein PM03, Putative NF-kappa-B-activating protein 209, Zinc finger DHHC domain-containing protein 13, DHHC-13) is encoded by the ZDHHC13 (also known as HIP14L, HIP3RP) gene (Gene ID: 54503) in human. DHHC-13 is a multi-pass membrane protein that serves as a palmitoyl acyltransferase (PAT) specific for a subset of neuronal proteins, including HD and GAD2 and may play a role in the pathogenesis of Huntington disease (HD). It is reported to be dysfunctional in the presence of the HD mutation and HIP-14 deficient mice are shown to develop features of HD. DHHC-13 also plays a role in cellular magnesium homeostasis. It contains a DHHC domain (aa 426-476 in isoform 1 and 250-300 in isoform 2), which is required for its palmitoyltransferase activity. (Ref.: Young, FB et al. (2011). Prog. Neurobiol. 97(2); 220-238).
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Applications
ApplicationAnti-ZDHHC13, clone 26D1, Cat. No. MABT1498, is a mouse monoclonal antibody that detects Palmitoyltransferase ZDHHC13 and has been tested for use in Western Blotting.
Key Applications
  • Western Blotting
Biological Information
ImmunogenMBP-tagged recombinant fragment corresponding to 111 amino acids from the N-terminal region of human Palmitoyltransferase ZDHHC13, isoform 2.
Clone26D1
ConcentrationPlease refer to lot specific datasheet.
HostMouse
SpecificityClone 26D1 detects human Palmitoyltransferase ZDHHC13. It targets an epitope within 111 amino acids from the N-terminal region of isoforms 1 and 2. This sequence is conserved in both isoforms.
IsotypeIgG1κ
Species Reactivity
  • Human
Species Reactivity NoteHuman.
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • ZDHHC13
  • HIP14L
  • HIP3RP
Purification MethodProtein G purified
UniProt Number
Molecular Weight~55 kDa observed; 56.51 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in A431 cell lysate.

Western Blotting Analysis: A 1:500 dilution of this antibody detected ZDHHC13 in A431 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABT1498-100UL 04054839563409