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AB3123 Anti-Tie-1 Antibody, CT

This Anti-Tie-1 Antibody, C-terminus is validated for use in ELISA, WB for the detection of Tie-1.

Anti-Tie-1 Antibody, CT MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Growth Factors & Receptors Gene Symbol: TIE1, JTK14, TIE, EC 2.7.10.1 UniProt Number: P35590
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AB3123
50 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
B, H, M, RELISA, WBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberAB3123
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-Tie-1 Antibody, CT
References
Product Information
FormatAffinity Purified
PresentationAffinity purified immunoglobulin. Liquid in PBS with 0.1% BSA and 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-Tie-1 Antibody, C-terminus is validated for use in ELISA, WB for the detection of Tie-1.
Key Applications
  • ELISA
  • Western Blotting
Application NotesWestern blot: 1-10 μg/mL using ECL. NIH/3T3 cells can be used as positive control. The predicted size of Tie-1 is ~135-140 kDa.

ELISA: (1:10,000 -1:100,000) using 50-100 ng of control peptide per well.

Optimal working dilutions must be determined by end user.
Biological Information
Immunogen20 amino acid peptide sequence within the cytoplasmic, C-terminus of human Tie-1.
EpitopeC-terminus
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityRecognizes human Tunica internal endothelial cell kinase (Tie-1), also described as tyrosine protein kinase receptor. Tie-1 (human 1138 aa; mouse 1134 aa) is a type 1 membrane receptor protein specifically expressed in developing vascular endothelial cells. Tie-1 extracellular portion (25-279 aa) contains 3 fibronectin type III-like and 2 Ig-like C2-type, and 3-EGF-like domains.

SPECIES REACTIVITIES: The peptide sequence used is 100% conserved in mouse, rat, and bovine. Antibody crossreactivity in other species is not established.
Species Reactivity
  • Bovine
  • Human
  • Mouse
  • Rat
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • TIE1
  • JTK14
  • TIE
  • EC 2.7.10.1
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P35590 # Probable protein tyrosine-kinase transmembrane receptor.
SIZE: 1138 amino acids; 125090 Da
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
TISSUE SPECIFICITY: Specifically expressed in developing vascular endothelial cells.
SIMILARITY: SwissProt: P35590 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. Tie subfamily. & Contains 3 EGF-like domains. & Contains 3 fibronectin type-III domains. & Contains 2 Ig-like C2-type (immunoglobulin-like) domains. & Contains 1 protein kinase domain.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain frozen at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze and thaw.
Packaging Information
Material Size50 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
AB3123 04053252337024

Documentation

Anti-Tie-1 Antibody, CT SDS

Title

Safety Data Sheet (SDS) 

Anti-Tie-1 Antibody, CT Certificates of Analysis

TitleLot Number
RABBIT ANTI-TIE-1 - 3541916 3541916
RABBIT ANTI-TIE-1 AFFINITY-PURIFIED 2470362
RABBIT ANTI-TIE-1 AFFINITY-PURIFIED POLYCLONAL ANTIBODY - 2117981 2117981
RABBIT ANTI-TIE-1 AFFINITY-PURIFIED POLYCLONAL ANTIBODY - 2435029 2435029
RABBIT ANTI-TIE-1 AFFINITY-PURIFIED -2552111 2552111
RABBIT ANTI-TIE-1 AFFINITY-PURIFIED -2571235 2571235
RABBIT ANTI-TIE-1 AFFINITY-PURIFIED POLYCLONAL ANTIBODY - 2026343 2026343
RABBIT ANTI-TIE-1 AFFINITY-PURIFIED POLYCLONAL ANTIBODY - 2074745 2074745
RABBIT ANTI-TIE-1 AFFINITY-PURIFIED POLYCLONAL ANTIBODY - 2270329 2270329

Data Sheet

Title
Anti-Tie-1, C-terminus - Data Sheet