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AB9328 Anti-Thioredoxin 1 Antibody

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AB9328
100 µL  
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Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
M, RWBRbSerumPolyclonal Antibody
Description
Catalogue NumberAB9328
ReplacesMABN1090
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-Thioredoxin 1 Antibody
Alternate Names
  • TRX1
References
Product Information
FormatSerum
PresentationRabbit serum. Liquid. Contains no preservative.
Quality LevelMQ100
Applications
ApplicationDetect Thioredoxin 1 using this Anti-Thioredoxin 1 Antibody validated for use in WB.
Key Applications
  • Western Blotting
Application NotesImmunoblotting: 1:1,000-1:5,000 using ECL. Reacts with the ~12-14 kD thioredoxin 1 protein. Additional bands >30 kD may been seen.

Suggested dilution and blocking buffer is TBST containing 5% non-fat milk. Suggested gel percentage is 15%. Suggested incubation time is overnight.
Biological Information
ImmunogenSynthetic peptide from rat/mouse Thioredoxin 1.
HostRabbit
SpecificityRecognizes Thioredoxin 1 (TRX1).
Species Reactivity
  • Mouse
  • Rat
Species Reactivity NoteIt is expected that the antibody will also react with human due to sequence homology (14/15).
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • Txn
  • Txn1
  • TRDX
  • TRX
  • TRX1
UniProt Number
UniProt SummaryFUNCTION: SwissProt: Q03164 # Possibly acts as a transcriptional regulatory factor.
SIZE: 3969 amino acids; 431764 Da
SUBUNIT: Interacts with SBF1.
SUBCELLULAR LOCATION: Nucleus.
TISSUE SPECIFICITY: Heart, lung, brain and T- and B-lymphocytes.
DISEASE: SwissProt: Q03164 # Chromosomal aberrations involving MLL are a cause of acute leukemias. Translocation t(1;11)(q21;q23) with MLLT11/AF1Q; translocation t(3;11)(p21;q23) with NCKIPSD/AF3p21; translocation t(3,11)(q25,q23) with GMPS; translocation t(4;11)(q21;q23) with AFF1/MLLT2/AF4; insertion ins(5;11)(q31;q13q23) with AFF4/AF5Q31; translocation t(5;11)(q12;q23) with AF5-alpha/CENPK; translocation t(6;11)(q27;q23) with MLLT4/AF6; translocation t(9;11)(p22;q23) with MLLT3/AF9; translocation t(10;11)(p11.2;q23) with ABI1; translocation t(10;11)(p12;q23) with MLLT10/AF10; t(11;15)(q23;q14) with CASC5 and ZFYVE19; translocation t(11;17)(q23;q21) with MLLT6/AF17; translocation t(11;19)(q23;p13.3) with ELL; translocation t(11;19)(q23;p13.3) with MLLT1/ENL; translocation t(11;19)(q23;p23) with GAS7; translocation t(X;11)(q13;q23) with FOXO4/AFX1. Translocation t(3;11)(q28;q23) with LPP. Translocation t(10;11)(q22;q23) with CXXC6. Translocation t(9;11)(q34;q23) with DAB2IP. Translocation t(4;11)(p12;q23) with FRYL. & A chromosomal aberration involving MLL may be a cause of chronic neutrophilic leukemia. Translocation t(4;11)(q21;q23) with SEPT11.
SIMILARITY: SwissProt: Q03164 ## Belongs to the TRX/MLL family. & Contains 3 A.T hook DNA-binding domains. & Contains 1 bromo domain. & Contains 1 CXXC-type zinc finger. & Contains 3 PHD-type zinc fingers. & Contains 1 post-SET domain. & Contains 1 SET domain.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
AB9328 04053252324673

Documentation

Anti-Thioredoxin 1 Antibody SDS

Title

Safety Data Sheet (SDS) 

Anti-Thioredoxin 1 Antibody Certificates of Analysis

TitleLot Number
RABBIT ANTI-THIOREDOXIN 1 POLYCLONAL ANTIBODY - 2393863 2393863
RABBIT ANTI-THIOREDOXIN 1 POLYCLONAL ANTIBODY - 2458994 2458994
RABBIT ANTI-THIOREDOXIN 1 -2889138 2889138
RABBIT ANTI-THIOREDOXIN 1 POLYCLONAL ANTIBODY 3048315
RABBIT ANTI-THIOREDOXIN 1 POLYCLONAL ANTIBODY 3098919
RABBIT ANTI-THIOREDOXIN 1 POLYCLONAL ANTIBODY - 1993751 1993751

Brochure

Title
Pathways and Biomarkers of Oxidative Stress

Technical Info

Title
White Paper- Modern Methods in Oxidative Stress Research

Data Sheet

Title
RABBIT ANTI-THIOREDOXIN 1