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ABF219 Anti-SARM Antibody

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ABF219
100 µg  
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Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, ICC, IFRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABF219
DescriptionAnti-SARM Antibody
Alternate Names
  • Sterile alpha and TIR motif-containing protein 1
  • Sterile alpha and Armadillo repeat protein
  • Sterile alpha motif domain-containing protein 2
  • SAM domain-containing protein 2
  • Tir-1 homolog
Background InformationSterile alpha and Armadillo repeat protein (SARM), also known as Sterile alpha and TIR motif-containing protein 1 (SARM1) and Sterile alpha motif domain-containing protein 2 (SAMD2), is involved in the innate immnune response. SARM blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction, without affecting the MYD88-dependent pathway or non-TLR signaling. SARM is expressed kidney and liver with lower levels found in placenta.
References
Product Information
FormatAffinity Purified
Control
  • Daudi cell lysate
PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect Sterile alpha & Armadillo repeat protein using this rabbit polyclonal antibody, Anti-SARM Antibody validated for use in western blotting, ICC & Immunofluorescence.
Key Applications
  • Western Blotting
  • Immunocytochemistry
  • Immunofluorescence
Application NotesImmunocytochemistry Analysis: 2 µg/mL from a representative lot detected SARM in Daudi cells.

Immunofluorescence Analysis: 2 µg/mL from a representative lot detected SARM in Daudi cells.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the C-terminus of human SARM.
EpitopeC-terminus
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody recognizes the C-terminus of SARM.
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Gene Symbol
  • SARM1
  • SAMD2
  • SARM
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~89 kDa observed. Uncharacterized bands may appear in some lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in Daudi cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected SARM in 15 µg of Daudi cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ABF219 04053252879913