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ABN334 Anti-SAPAP4 Antibody

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ABN334
100 µg  
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Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, RWB, IHCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABN334
DescriptionAnti-SAPAP4 Antibody
Alternate Names
  • SAPAP4
  • SAP90
  • PSD-95-associated protein 4
  • Disks large-associated protein 4
  • DLGAP4
  • DAP4
Background InformationSAP90/PSD-95-associated protein 4 (SAPAP4, also known as DLGAP4) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP4 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). SAPAP4 mRNA is targeted to cell bodies in a similar manner to SAPAP1 and -2, whereas SAPAP3 mRNA is detected mainly in cell bodies. At least three isoforms of SAPAP4 are known to exist.
References
Product Information
FormatAffinity Purified
Control
  • SK-N-SH cell lysate
PresentationPurified rabbit polyclonal in buffer containing PBS with 0.02% sodium azide.
Quality LevelMQ300
Applications
ApplicationThis SAPAP4 antibody is validated for use in WB & IHC for the detection of the SAPAP4 protein.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:500 dilution from a representative lot detected SAPAP4 in rat hippocampus tissue.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human SAPAP4.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis SAPAP4 antibody will not cross-react with other SAPAP proteins.
Species Reactivity
  • Human
  • Rat
Antibody TypePolyclonal Antibody
Gene Symbol
  • DLGAP4
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~138 kDa observed. The calculated molecular weight of this protein is 109 kDa, but can be observed at ~138 kDa due to post translational modification.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in SK-N-SH cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected SAPAP4 in 15 µg/mL of SK-N-SH cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ABN334 04053252831140