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MAB5296 Anti-Oxytocin Antibody, clone 4G11

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MAB5296
100 µL  
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Overview

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, RELISA, IHCMAscitesMonoclonal Antibody
Description
Catalogue NumberMAB5296
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-Oxytocin Antibody, clone 4G11
Product Information
FormatAscites
Control
  • Pituitary Gland
PresentationAscites fluid without any preservative.
Quality LevelMQ100
Applications
ApplicationThis Anti-Oxytocin Antibody, clone 4G11 is validated for use in ELISA, IH for the detection of Oxytocin.
Key Applications
  • ELISA
  • Immunohistochemistry
Application NotesImmunohistochemistry on 4% paraformaldehyde fixed frozen tissue: 1:5,000-1:10,000.

ELISA: 1:1,000,000

Optimal working dilutions must be determined by the end user.
Biological Information
ImmunogenOxytocin conjugated to thyroglobulin.
Clone4G11
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
SpecificityRecognizes Oxytocin. No reactivity to arginine vasopressin, vasotocin or [Asu1,6,Arg8]-vasopressin by competitive ELISA.
IsotypeIgG1
Species Reactivity
  • Human
  • Rat
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThere are two proteins encoded by this gene, oxytocin and neurophysin I. Oxytocin is posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions.
Gene Symbol
  • OXT
  • MGC126890
  • MGC126892
  • OT
  • OT-NPI
Purification MethodUnpurified
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P01178 # Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland.
SIZE: 125 amino acids; 12722 Da
SUBCELLULAR LOCATION: Secreted.
SIMILARITY: SwissProt: P01178 ## Belongs to the vasopressin/oxytocin family.
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Packaging Information
Material Size100 µL
Global Trade Item Number
Catalogue Number GTIN
MAB5296 04053252266683