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MABN92-AF488 Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor® 488 Conjugate

Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor® 488 Conjugate is an antibody against Iba1/AIF1 for use in Immunohistochemistry.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Neuroscience Gene Symbol: AIF1, G1, IBA1 UniProt Number: P55008
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MABN92-AF488
100 µL  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, M, RIHCMAlexaFluor®488Monoclonal Antibody
Description
Catalogue NumberMABN92-AF488
DescriptionAnti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor® 488 Conjugate
Alternate Names
  • Allograft inflammatory factor 1
  • AIF-1
  • Daintain
  • Interferon gamma responsive transcript
  • Ionized calcium-binding adapter molecule 1
  • Protein G1
Background InformationAllograft inflammatory factor 1 (UniProt P55008; also known as AIF-1, Daintain, Interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, Protein G1) is encoded by the AIF1 (also known as G1, IBA1) gene (Gene ID 199) in human. Iba1/AIF1 is a 17 kDa interferon-gamma- (IFN-gamma-) inducible, Ca(2+)-binding EF-hand protein. Iba1/AIF1 expression is mostly limited to the macrophage/monocyte lineage, and is augmented by cytokines, such as IFN-gamma. It is reported to be involved in neuronal function, inflammatory responses, allograft rejection, autoimmunity, and macrophage activation/function. It is also shown to be expressed in microglial cells in autominnume disesase models such as experimental autoimmune encephalomyelitis, neuritis and uveitis.
References
Product Information
FormatAlexaFluor®488
PresentationPurified mouse antibody conjugate in PBS with 15 mg/mL BSA and 0.1 % sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor® 488 Conjugate is an antibody against Iba1/AIF1 for use in Immunohistochemistry.
Key Applications
  • Immunohistochemistry
Application NotesThe unconjugated antibody (Cat. No. MABN92) is shown to be suitable also for Western blotting and immunohistochemistry applications.
Biological Information
ImmunogenLinear peptide corresponding to a human Iba1/AIF1 sequence.
Clone20A12.1
ConcentrationPlease refer to lot specific datasheet.
HostMouse
IsotypeIgG1κ
Species Reactivity
  • Human
  • Mouse
  • Rat
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • AIF1
  • G1
  • IBA1
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~17 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Immunohistochemistry in human spleen tissue.

Immunohistochemistry Analysis: A 1:300 dilution of this antibody detected Iba1/AIF1 in human spleen tissue.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABN92-AF488 04055977301229

Documentation

Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor® 488 Conjugate SDS

Title

Safety Data Sheet (SDS) 

Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor® 488 Conjugate Certificates of Analysis

TitleLot Number
Anti-Iba1/AIF1, clone 20A12.1, -2819311 2819311
Anti-Iba1/AIF1, clone 20A12.1, -Q2631260 Q2631260
Anti-Iba1/AIF1, clone 20A12.1, Alexa Fluor® 488 Conjugate - 3191412 3191412
Anti-Iba1/AIF1, clone 20A12.1, Alexa Fluor® 488 Conjugate - 3328184 3328184
Anti-Iba1/AIF1, clone 20A12.1, Alexa Fluor® 488 Conjugate - 3474116 3474116
Anti-Iba1/AIF1, clone 20A12.1, Alexa Fluor® 488 Conjugate - 3541886 3541886
Anti-Iba1/AIF1, clone 20A12.1, Alexa Fluor® 488 Conjugate - 3700875 3700875
Anti-Iba1/AIF1, clone 20A12.1, Alexa Fluor® 488 Conjugate - 3764705 3764705
Anti-Iba1/AIF1, clone 20A12.1, Alexa Fluor® 488 Conjugate - 3841496 3841496
Anti-Iba1/AIF1, clone 20A12.1, Alexa Fluor® 488 Conjugate - 3942835 3942835
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Brochure

Title
Neuroscience Solutions for productive research