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ABT333 Anti-IL-1RAcP Antibody

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ABT333
100 µg  
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Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, ICCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABT333
DescriptionAnti-IL-1RAcP Antibody
Alternate Names
  • IL-1RAcP
  • C3orf13
  • IL1R3
  • Interleukin-1 receptor accessory protein
  • IL-1 receptor accessory protein
  • IL-1RAcP
  • Interleukin-1 receptor 3
Background InformationInterleukin-1 receptor accessory protein (IL-1RAcP), also known as Interleukin-1 receptor 3 (IL-1R-3, IL-1R3) forms a complex with IL-1RI in response to IL-1 treatment. The IL-1 receptor-associated kinase (IRAK), which mediates activation of NF-kB inducing kinae (NIK) and of NF-kB, recruites to the IL-1R complex through IL-1 RAcP. IL-1 activation of stress-activated protein kinase and of acid sphingomyelinase also requires IL-1RAcP. Like IL-1RI, IL-1RAcP subunit is essential for IL-1 mediated cellular response. IL-1RAcP is expressed in many tissues.
References
Product Information
FormatAffinity Purified
Control
  • HeLa cell lysate
PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect Interleukin Receptor using this rabbit polyclonal antibody, Anti-IL-1RAcP Antibody validated for use in western blotting & ICC.
Key Applications
  • Western Blotting
  • Immunocytochemistry
Application NotesImmunocytochemistry Analysis: 5 ug/mL from a representative lot detected IL-1RAcP in HeLa cells.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the C-terminus of human IL-1RAcP.
EpitopeC-terminus
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody recognizes the C-terminus of IL-1RAcP.
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Gene Symbol
  • IL1RAP
  • IL-1R-3
  • IL-1R3
  • IL1RAP
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~66 kDa observed. Uncharacterized bands may appear in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in HeLa cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected IL-1RAcP in 15 µg of HeLa cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ABT333 04053252910241