Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

ABN342 Anti-FEZ2 Antibody

Detect the FEZ2 protein using this Anti-FEZ2 validated for use in WB & IF.

Anti-FEZ2 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience, Neuroscience Research Sub-Category: Developmental Neuroscience, Neuroregenerative Medicine Gene Symbol: FEZ2 UniProt Number: Q9UHY8
View Products on Sigmaaldrich.com
ABN342
100 µg  
Purchase on Sigma-Aldrich

Special Offers

Overview

Replacement Information

Special Offers

100% Performance Guaranteed

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
M, HWB, IFRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABN342
DescriptionAnti-FEZ2 Antibody
Alternate Names
  • Fasciculation and elongation protein zeta-2
  • Zygin II
  • Zygin-2
Background InformationFasciculation and elongation protein zeta-2 (FEZ2) is a homolog to the mammalian FEZ1, itself an ortholog of the C. elegans UNC-76. In contrast to FEZ1, FEZ2 mRNA is widely expressed in mouse tissues. FEZ2 interacts with protein kinase C (PKC)-zeta substrate and induces neurite extension of PC12 cells when co-expressed with a constitutively active form of PKC-zeta, suggesting FEZ2 may play an important role in the morphological changes of various cells by associating with PKC-zeta in a tissue non-specific manner. FEZ2 can interact with FEZ1 through its c-terminal regions and especially its coiled-coil region. At least two isoforms of FEZ2 are known to exist.
References
Product Information
FormatAffinity Purified
Control
  • 3T3 cell lysate
PresentationPurified rabbit polyclonal in buffer containing PBS with 0.02% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect the FEZ2 protein using this Anti-FEZ2 validated for use in WB & IF.
Key Applications
  • Western Blotting
  • Immunofluorescence
Application NotesImmunofluorescence Analysis: 5 µg/mLfrom a representative lot detected FEZ2 in human brain tissue.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human FEZ2.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
IsotypeIgG
Species Reactivity
  • Mouse
  • Human
Antibody TypePolyclonal Antibody
Gene Symbol
  • FEZ2
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~38/50 kDa observed. An uncharacterized band may appear at ~48 kDa in some lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in 3T3 cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected FEZ2 in 15 µg of 3T3 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ABN342 04053252847431