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ABC257 Anti-EPHB4 Antibody

Detect EphB4 using this rabbit polyclonal antibody, Anti-EPHB4 Antibody validated for use in western blotting.

Anti-EPHB4 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: EPHB4, HTK, MYK1, TYRO11 UniProt Number: P54760
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ABC257
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABC257
DescriptionAnti-EPHB4 Antibody
Alternate Names
  • Ephrin type-B receptor 4
  • Hepatoma transmembrane kinase
  • Tyrosine-protein kinase TYRO11
Background InformationEphrin type-B receptor 4 (EPHB4) is also called Hepatoma transmembrane kinase, and Tyrosine-protein kinase TYRO11. EPHB4 is a receptor tyrosine kinase that together with EFNB2 is critical to heart morphogenesis and angiogenesis through the regulation of cell adhesion and cell migration. EPHB4 is expressed in placenta, kidney, liver, lung, pancreas, skeletal muscle, and heart, as well as primitive and myeloid hematopoietic cells.
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect EphB4 using this rabbit polyclonal antibody, Anti-EPHB4 Antibody validated for use in western blotting.
Key Applications
  • Western Blotting
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the cytoplasmic domain of human EPHB4.
EpitopeCytoplasmic domain
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
Species Reactivity
  • Human
Species Reactivity Note Predicted to react with Mouse, Rat, and Bovine based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • EPHB4
  • HTK
  • MYK1
  • TYRO11
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~120 kDa observed. The calculated molecular weight is 108 kDa, however EPHB4 has been shown as a ~120 kDa band in western blots (Lee, Y. C., et al. (2005). BMC Cancer. 5(119):1-11).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in PC3 tissue lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected EPHB4 in 10 µg of PC3 tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ABC257 04053252920653