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288104 2ʹ,5ʹ-Dideoxyadenosine - CAS 6698-26-6 - Calbiochem

Overview

Key Spec Table

CAS #Empirical Formula
6698-26-6C₁₀H₁₃N₅O₂

Products

Catalogue NumberPackaging Qty/Pack
288104-1MG Plastic ampoule 1 mg
Description
OverviewCell-permeable, non-competitive adenylate cyclase inhibitor (IC50 = 3 µM), that binds to the adenosine P1 binding site. Blocks positive inotropic and chronotropic effects of β-adrenergic agents.
Catalogue Number288104
Brand Family Calbiochem®
Synonyms2ʹ,5ʹ-dd-Ado
References
ReferencesIbrahimi, A., et al. 1999. Am. J. Physiol. 276, C487.
Hartman, M., and Schrader, J. 1995. J. Mol. Cell. Cardiol. 25, 331.
Bushfield, M., et al. 1990. Mol. Pharmacol. 38, 848.
Reid, I.R., et al. 1990. Am. J. Physiol. 258, E708.
Legrand, A.B., et al. 1990. Biochem. Pharmacol. 40, 1103.
Johnson, R.A., et al. 1989. Mol. Pharmacol. 35, 681.
Holgate, S.T., et al. 1980. Proc. Natl. Acad. Sci. USA 77, 6800.
Product Information
CAS number6698-26-6
ATP CompetitiveN
FormWhite solid
Hill FormulaC₁₀H₁₃N₅O₂
Chemical formulaC₁₀H₁₃N₅O₂
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary Targetadenylate cyclase
Primary Target IC<sub>50</sub>3 µM against adenylate cyclase
Purity≥98% by HPLC
Physicochemical Information
Cell permeableY
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Global Trade Item Number
Catalogue Number GTIN
288104-1MG 04055977197914