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538927 15d-PGJ₂ - CAS 87893-55-8 - Calbiochem

Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
87893-55-8C₂₀H₂₈O₃

Products

Catalogue NumberPackaging Qty/Pack
538927-1MG Plastic ampoule 1 mg
Description
OverviewA metabolite of PGD2 that has recently been identified as a natural ligand for PPARγ-dependent adipogenesis in transfected NIH/3T3 cells and for PPARγ response element (PPRE) in CV-1 cells. Competes with thiazolidinediones for PPARγ binding. Down-regulates inducible nitric oxide synthase (iNOS).
Catalogue Number538927
Brand Family Calbiochem®
SynonymsProstaglandin J₂, 15-Deoxy-Δ12,14, PPAR Agonist VII, PPARγ Agonist VI
References
ReferencesPetrova, T.V., et al. 1999. Proc. Natl. Acad. Sci. USA 96, 4668.
Ricote, M., et al. 1998. Nature 391, 79.
Forman, B.M., et al. 1995. Cell 83, 803.
Kliewer, S.A., et al. 1995. Cell 83, 813.
Product Information
CAS number87893-55-8
ATP CompetitiveN
FormOil
Hill FormulaC₂₀H₂₈O₃
Chemical formulaC₂₀H₂₈O₃
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetA natural ligand for PPARγ-dependent adipogenesis
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 20/21/22

Harmful by inhalation, in contact with skin and if swallowed.
S PhraseS: 36

Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Harmful
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
538927-1MG 04055977195279

Documentation

15d-PGJ₂ - CAS 87893-55-8 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

15d-PGJ₂ - CAS 87893-55-8 - Calbiochem Certificates of Analysis

TitleLot Number
538927

References

Reference overview
Petrova, T.V., et al. 1999. Proc. Natl. Acad. Sci. USA 96, 4668.
Ricote, M., et al. 1998. Nature 391, 79.
Forman, B.M., et al. 1995. Cell 83, 803.
Kliewer, S.A., et al. 1995. Cell 83, 813.

Brochure

Title
Bioactive Lipids Technical Bulletin
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision15-July-2016 JSW
SynonymsProstaglandin J₂, 15-Deoxy-Δ12,14, PPAR Agonist VII, PPARγ Agonist VI
DescriptionA metabolite of PGD2 that has recently been identified as a natural ligand for PPARγ-dependent adipogenesis in transfected 3T3 cells and for PPARγ response element (PPRE) in CV-1 cells. Competes with thiazolidinediones for PPARγ binding.
FormOil
Intert gas (Yes/No) Packaged under inert gas
CAS number87893-55-8
Chemical formulaC₂₀H₂₈O₃
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityDMSO (25 mg/ml) or ethanol (25 mg/ml)
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Harmful
ReferencesPetrova, T.V., et al. 1999. Proc. Natl. Acad. Sci. USA 96, 4668.
Ricote, M., et al. 1998. Nature 391, 79.
Forman, B.M., et al. 1995. Cell 83, 803.
Kliewer, S.A., et al. 1995. Cell 83, 813.