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596200 Thioflavin T - CAS 2390-54-7 - Calbiochem

A cell-permeable benzothiazole dye that exhibits enhanced fluorescence upon binding to amyloid fibrils.

Thioflavin T - CAS 2390-54-7 - Calbiochem : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: ThT, Thioflavine T, Basic Yellow 1

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596200
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Tableau de caractéristiques principal

CAS #Empirical Formula
2390-54-7C₁₇H₁₉ClN₂S

Prix & Disponibilité

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596200-500MG
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      		 Ampoule plast. 500 mg
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      Description
      OverviewA cell-permeable benzothiazole dye that exhibits enhanced fluorescence upon binding to amyloid fibrils. Useful in monitoring stacked β sheet aggregates.
      Catalogue Number596200
      Brand Family Calbiochem®
      SynonymsThT, Thioflavine T, Basic Yellow 1
      References
      ReferencesTjernberg, L.O., et al. 1999. J. Biol. Chem. 274, 12619.
      Naiki, H. and Nakakuki, K. 1996. Lab. Invest. 74, 374.
      LeVine, H. 1993. Protein Sci. 2, 404.
      Product Information
      CAS number2390-54-7
      ATP CompetitiveN
      FormYellow solid
      Hill FormulaC₁₇H₁₉ClN₂S
      Chemical formulaC₁₇H₁₉ClN₂S
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetExhibits enhanced fluorescence upon binding to amyloid fibrils
      Physicochemical Information
      Cell permeableY
      Emission max.
      Excitation max.
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +15°C to +30°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      596200-500MG 04055977189131

      Documentation

      Thioflavin T - CAS 2390-54-7 - Calbiochem FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      Thioflavin T - CAS 2390-54-7 - Calbiochem Certificats d'analyse

      TitreNuméro de lot
      596200

      Références bibliographiques

      Aperçu de la référence bibliographique
      Tjernberg, L.O., et al. 1999. J. Biol. Chem. 274, 12619.
      Naiki, H. and Nakakuki, K. 1996. Lab. Invest. 74, 374.
      LeVine, H. 1993. Protein Sci. 2, 404.

      Brochure

      Titre
      Alzheimer's Disease Brochure & Technical Guide
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision12-September-2008 RFH
      SynonymsThT, Thioflavine T, Basic Yellow 1
      DescriptionA cell-permeable benzothiazole dye that exhibits enhanced fluorescence upon binding to amyloid fibrils. Useful in monitoring stacked β sheet aggregates. Associates with aggregated fibrils of synthetic β/A4-derived peptides β(1-28) and β(1-40), resulting in a shift in the excitation maximum and an enhanced emission. Excitation max.: ~385 nm (free); ~437 nm (bound); emission max.: ~445 nm (free); ~485 nm (bound).
      FormYellow solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number2390-54-7
      Chemical formulaC₁₇H₁₉ClN₂S
      Structure formulaStructure formula
      SolubilityH₂O (5 mg/ml)
      Storage Protect from light
      +15°C to +30°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesTjernberg, L.O., et al. 1999. J. Biol. Chem. 274, 12619.
      Naiki, H. and Nakakuki, K. 1996. Lab. Invest. 74, 374.
      LeVine, H. 1993. Protein Sci. 2, 404.