Millipore Sigma Vibrant Logo

529505 PON1 Activator, ZNPA - CAS 42172-66-7 - Calbiochem

Aperçu

Tableau de caractéristiques principal

CAS #Empirical Formula
42172-66-7C₁₅H₉N₃O₄

Prix & Disponibilité

Référence DisponibilitéConditionnement Qté Prix Quantité
529505-10MG
Disponibilité limitée
Disponibilité limitée
En stock 
Interrompu(e)
Disponible en quantités limitées
Disponibilité à confirmer
    Pour le restant : Nous vous tiendrons informé
      Pour le restant : Nous vous tiendrons informé
      Nous vous tiendrons informé
      Contacter le Service Clients
      Contact Customer Service

      Flacon en verre 10 mg
      Le prix n'a pas pu être récupéré
      La quantité minimale doit être un multiple de
      Maximum Quantity is
      À la validation de la commande Plus d'informations
      Vous avez sauvegardé ()
       
      Demander le prix
      Description
      OverviewA cell-permeable stilbene derivative that serves as an aryl hydrocarbon receptor (AhR) ligand and acts as a highly specific and potent inducer of paraoxonase 1 (PON1). Shown to be a better activator of PON1 mRNA (EC50 = 1 µM) and inducer of PON1 enzymatic activity (> 3 fold at 5 µM) when compared to resveratrol (Cat. No. 554325). However, it is devoid of any activity against estrogen receptors and is not shown to inhibit activity of tyrosine kinases. Also shown to antagonize the effects of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) on cytochrome P450 1A1 (CYP1A1).
      Catalogue Number529505
      Brand Family Calbiochem®
      Synonyms(Z)-2,3-bis (4-nitrophenyl)-acrylonitrile
      References
      ReferencesGuyot, E., et al. 2011. Biochem. Pharm. 83, 627.
      Product Information
      CAS number42172-66-7
      FormPale yellow solid
      Hill FormulaC₁₅H₉N₃O₄
      Chemical formulaC₁₅H₉N₃O₄
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Purity≥99% by HPLC
      Storage and Shipping Information
      Ship Code Shipped with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      Référence GTIN
      529505-10MG 04055977269673