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459618 Okadaic Acid, Potassium Salt - CAS 155751-72-7 - Calbiochem

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Tableau de caractéristiques principal

CAS #Empirical Formula
155751-72-7C₄₄H₆₇ O₁₃ · K

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459618-50UG
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      Description
      OverviewWater-soluble analog of Okadaic Acid (Cat. No. 495604). Inhibits protein phosphatases 1 and 2A.
      Catalogue Number459618
      Brand Family Calbiochem®
      References
      ReferencesGjertsen, B.T., et al. 1994. J. Cell Sci. 107, 3363.
      Kiguchi, K., et al. 1994. Cell Growth Differ. 5, 995.
      Ohaka, Y., et al. 1993. Biochem. Biophys. Res. Commun. 197, 916.
      Gopalakrishna, R., et al. 1992. Biochem. Biophys. Res. Commun. 189, 950.
      Kreienbuhl, P., et al. 1992. Blood 80, 2911.
      Nomura, M., et al. 1992. Biochemistry 31, 11915.
      Song, Q., et al. 1992. J. Cell Physiol. 153, 550.
      Tada, Y., et al. 1992. Immunopharmacol. 24, 17.
      Product Information
      CAS number155751-72-7
      ATP CompetitiveN
      FormClear colorless solid film
      Hill FormulaC₄₄H₆₇ O₁₃ · K
      Chemical formulaC₄₄H₆₇ O₁₃ · K
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      ApplicationOkadaic Acid, Potassium Salt, CAS 155751-72-7, is a water-soluble analog of Okadaic Acid (Cat. No. 495604). A potent inhibitor of protein phosphatase 1 (IC50 = 10-15 nM) and 2A (IC50 = 0.1 nM).
      Biological Information
      Primary TargetPP1, PP2
      Primary Target IC<sub>50</sub>10-15 nM, 0.1 nM, against protein phosphatase 1 and protein phosphatase 2A, respectively
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Safety Information
      R PhraseR: 23/24/25-38

      Toxic by inhalation, in contact with skin and if swallowed.
      Irritating to skin.
      S PhraseS: 22-26-36/37/39-45

      Do not breathe dust.
      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing, gloves and eye/face protection.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Toxic
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Global Trade Item Number
      Référence GTIN
      459618-50UG 04055977185294