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200488 InSolution™Bestatin, Hydrochloride - Calbiochem

A metalloprotease inhibitor. Reversibly binds to cell surfaces and competitively inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase.

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: [(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-Leu, HCl

Primary Target: Metalloproteases
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200488
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Aperçu

Replacement Information

Tableau de caractéristiques principal

Empirical Formula
C₁₆H₂₄N₂O₄ • HCl

Prix & Disponibilité

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200488-10MG
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      Description
      OverviewA metalloprotease inhibitor. Reversibly binds to cell surfaces and competitively inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. Also acts as a potent aminopeptidase N inhibitor. Activates macrophages and T lymphocytes. Has anti-tumor properties. Effective at a concentration of 1-10 µM. The solid form of this compound (Cat. No. 200484) is also available.
      Catalogue Number200488
      Brand Family Calbiochem®
      Synonyms[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-Leu, HCl
      References
      ReferencesMerck Index: 14, 9842.
      Inoue, T., et al. 1994. J. Clin. Endocrinol. Metab. 79, 171.
      Taylor, A., et al. 1993. Biochemistry 32, 784.
      Ishida, J.I., et al. 1984. J. Chromatogr. 305, 381.
      Umezawa, H. 1982. Annu. Rev. Microbiol. 36, 75.
      Product Information
      FormLiquid
      FormulationSupplied as a 50 mM (10 mg/580 µL) solution of Bestatatin, HCl in H₂O.
      Hill FormulaC₁₆H₂₄N₂O₄ • HCl
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetMetalloproteases
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      200488-10MG 04055977221510

      Documentation

      InSolution™Bestatin, Hydrochloride - Calbiochem FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      InSolution™Bestatin, Hydrochloride - Calbiochem Certificats d'analyse

      TitreNuméro de lot
      200488

      Références bibliographiques

      Aperçu de la référence bibliographique
      Merck Index: 14, 9842.
      Inoue, T., et al. 1994. J. Clin. Endocrinol. Metab. 79, 171.
      Taylor, A., et al. 1993. Biochemistry 32, 784.
      Ishida, J.I., et al. 1984. J. Chromatogr. 305, 381.
      Umezawa, H. 1982. Annu. Rev. Microbiol. 36, 75.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision21-September-2012 JSW
      Synonyms[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-Leu, HCl
      DescriptionA metalloprotease inhibitor. Reversibly binds to cell surfaces and competitively inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. Also acts as a potent aminopeptidase N inhibitor. Activates macrophages and T lymphocytes. Has anti-tumor properties. Effective at a concentration of 1-10 µM. The solid form of this compound (Cat. No. 200484) is also available.
      FormLiquid
      FormulationSupplied as a 50 mM (10 mg/580 µL) solution of Bestatatin, HCl in H₂O.
      Intert gas (Yes/No) Packaged under inert gas
      Structure formulaStructure formula
      Purity≥98% by HPLC
      Storage Protect from light
      Avoid freeze/thaw
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesMerck Index: 14, 9842.
      Inoue, T., et al. 1994. J. Clin. Endocrinol. Metab. 79, 171.
      Taylor, A., et al. 1993. Biochemistry 32, 784.
      Ishida, J.I., et al. 1984. J. Chromatogr. 305, 381.
      Umezawa, H. 1982. Annu. Rev. Microbiol. 36, 75.