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508773 InSolution™ PPACK, 2HCl - CAS 82188-90-7 - Calbiochem

A 25 mM (5 mg/357 µl) sterile-filtered solution of PPACK, 2HCl in H₂O.

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: D-Phenylalanyl-L-prolyl-L-arginine chloromethyl ketone, 2HCl, H-D-Phe-Pro-Arg-chloromethylketone, 2HCl, PPACK, dihydrochloride InSolution™

Primary Target: Thrombin
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508773
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Replacement Information

Tableau de caractéristiques principal

CAS #Empirical Formula
82188-90-7C₂₁H₃₁ClN₆O₃ • 2HCl

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      Description
      Catalogue Number508773
      Brand Family Calbiochem®
      SynonymsD-Phenylalanyl-L-prolyl-L-arginine chloromethyl ketone, 2HCl, H-D-Phe-Pro-Arg-chloromethylketone, 2HCl, PPACK, dihydrochloride InSolution™
      References
      ReferencesRosado, J. A., et al. 2002. J. Biol. Chem. 277, 42157.
      Odake S., et al. 1995. J. Enzyme Inhib. 9, 17.
      Arni, R.K., et al. 1993. Biochemistry 32, 4727.
      Yamashita, T., et al. 1993. Thromb. Res. 69, 93.
      Schmaier, A.H., et al. 1992. Thromb. Res. 67, 479.
      Collen, D., et al. 1982. J. Lab. Clin. Med. 99, 76.
      Kettner, C., and Shaw, E. 1981. Methods Enzymol. 80, 826.
      Kettner, C., and Shaw, E. 1979. Thromb. Res. 14, 969.
      Product Information
      CAS number82188-90-7
      FormLiquid
      FormulationA 25 mM (5 mg/357 µl) sterile-filtered solution of PPACK, 2HCl (Cat. No. 520222) in H₂O.
      Hill FormulaC₂₁H₃₁ClN₆O₃ • 2HCl
      Chemical formulaC₂₁H₃₁ClN₆O₃ • 2HCl
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Target Thrombin
      Purity≥88% by HPLC
      Physicochemical Information
      Peptide SequenceH-D-Phe-Pro-Arg-chloromethylketone, 2HCl
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Protect from Light Protect from light
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      5087730001 04055977261394

      Documentation

      InSolution™ PPACK, 2HCl - CAS 82188-90-7 - Calbiochem FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      InSolution™ PPACK, 2HCl - CAS 82188-90-7 - Calbiochem Certificats d'analyse

      TitreNuméro de lot
      508773

      Références bibliographiques

      Aperçu de la référence bibliographique
      Rosado, J. A., et al. 2002. J. Biol. Chem. 277, 42157.
      Odake S., et al. 1995. J. Enzyme Inhib. 9, 17.
      Arni, R.K., et al. 1993. Biochemistry 32, 4727.
      Yamashita, T., et al. 1993. Thromb. Res. 69, 93.
      Schmaier, A.H., et al. 1992. Thromb. Res. 67, 479.
      Collen, D., et al. 1982. J. Lab. Clin. Med. 99, 76.
      Kettner, C., and Shaw, E. 1981. Methods Enzymol. 80, 826.
      Kettner, C., and Shaw, E. 1979. Thromb. Res. 14, 969.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision01-September-2017 JSW
      SynonymsD-Phenylalanyl-L-prolyl-L-arginine chloromethyl ketone, 2HCl, H-D-Phe-Pro-Arg-chloromethylketone, 2HCl, PPACK, dihydrochloride InSolution™
      DescriptionExtremely potent and selective irreversible inhibitor of thrombin (Kobs/[I] = 107M-1S-1). Reacts with thrombin in a 1:1 stoichiometry. Can also be used to inhibit tissue plasminogen activator. Factor VIIa, and Factor XIa.
      FormLiquid
      FormulationA 25 mM (5 mg/357 µl) sterile-filtered solution of PPACK, 2HCl (Cat. No. 520222) in H₂O.
      Intert gas (Yes/No) Packaged under inert gas
      CAS number82188-90-7
      Chemical formulaC₂₁H₃₁ClN₆O₃ • 2HCl
      Peptide SequenceH-D-Phe-Pro-Arg-chloromethylketone, 2HCl
      Purity≥88% by HPLC
      Storage Protect from light
      Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesRosado, J. A., et al. 2002. J. Biol. Chem. 277, 42157.
      Odake S., et al. 1995. J. Enzyme Inhib. 9, 17.
      Arni, R.K., et al. 1993. Biochemistry 32, 4727.
      Yamashita, T., et al. 1993. Thromb. Res. 69, 93.
      Schmaier, A.H., et al. 1992. Thromb. Res. 67, 479.
      Collen, D., et al. 1982. J. Lab. Clin. Med. 99, 76.
      Kettner, C., and Shaw, E. 1981. Methods Enzymol. 80, 826.
      Kettner, C., and Shaw, E. 1979. Thromb. Res. 14, 969.