Millipore Sigma Vibrant Logo

361556 GSK-3 Inhibitor IX, Control, MeBIO - CAS 710323-61-8 - Calbiochem

The GSK-3 Inhibitor IX, Control, MeBIO, also referenced under CAS 710323-61-8, controls the biological activity of GSK-3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: 1-Methyl-BIO

Primary Target: Relevant kinase inactive control
View Products on Sigmaaldrich.com
361556
Voir les Prix & la Disponibilité

Aperçu

Replacement Information

Tableau de caractéristiques principal

CAS #Empirical Formula
710323-61-8C₁₇H₁₂BrN₃O₂

Prix & Disponibilité

Référence DisponibilitéConditionnement Qté Prix Quantité
361556-1MG
Récupération des données relatives à la disponibilité...
—
Disponibilité limitée Disponibilité limitée
En stock 
Interrompu(e)
Disponible en quantités limitées
Disponibilité à confirmer
    Pour le restant : Nous vous tiendrons informé
      Pour le restant : Nous vous tiendrons informé
      Nous vous tiendrons informé
      Contacter le Service Clients
      Contact Customer Service

      		 Ampoule plast. 1 mg
      Prix en cours de récupération
      Le prix n'a pas pu être récupéré
      La quantité minimale doit être un multiple de
      Maximum Quantity is
      À la validation de la commande Plus d'informations
      Vous avez sauvegardé ()
       
      —
      Demander le prix
      		 —
      Description
      OverviewA cell-permeable N-methylated analog of GSK-3 Inhibitor IX, BIO (Cat. No. 361550) that serves as a relevant kinase inactive control (IC50 > 92 µM for Cdk1/B, > 100 µM for Cdk5/p25, and GSK-3α/β). Acts as a potent ligand for aryl hydrocarbon receptor (AhR; EC50 = 20 nM and 93 nM for yeast and hepatoma reporter systems, respectively) and displays antiproliferative properties.
      Catalogue Number361556
      Brand Family Calbiochem®
      Synonyms1-Methyl-BIO
      References
      ReferencesKnockaert, M., et al. 2004. Oncogene 23, 4400.
      Polychronopoulos, P., et al. 2004. J. Med. Chem. 47, 935.
      Meijer, L., et al. 2003. Chem. Biol. 10, 1255.
      Product Information
      CAS number710323-61-8
      ATP CompetitiveN
      FormDark red solid
      Hill FormulaC₁₇H₁₂BrN₃O₂
      Chemical formulaC₁₇H₁₂BrN₃O₂
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetRelevant kinase inactive control
      Primary Target IC<sub>50</sub>> 92 µM for Cdk1/B, > 100 µM for Cdk5/p25, and GSK-3α/β
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      361556-1MG 04055977214161

      Documentation

      GSK-3 Inhibitor IX, Control, MeBIO - CAS 710323-61-8 - Calbiochem FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      GSK-3 Inhibitor IX, Control, MeBIO - CAS 710323-61-8 - Calbiochem Certificats d'analyse

      TitreNuméro de lot
      361556

      Références bibliographiques

      Aperçu de la référence bibliographique
      Knockaert, M., et al. 2004. Oncogene 23, 4400.
      Polychronopoulos, P., et al. 2004. J. Med. Chem. 47, 935.
      Meijer, L., et al. 2003. Chem. Biol. 10, 1255.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision12-April-2011 RFH
      Synonyms1-Methyl-BIO
      DescriptionA cell-permeable N-methylated analog of GSK-3 Inhibitor IX, BIO (Cat. No. 361550) that serves as an inactive control for Cdk1/cyclin B, Cdk5/p25, and GSK-3α/β (IC50 >92 µM for Cdk1/cyclin B, >100 µM for Cdk5/p25, and GSK-3α/β). Acts as a potent ligand for aryl hydrocarbon receptor (AhR; EC50 = 20 nM and 93 nM for yeast and hepatoma reporter systems, respectively) and displays antiproliferative properties.
      FormDark red solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number710323-61-8
      Chemical formulaC₁₇H₁₂BrN₃O₂
      Structure formulaStructure formula
      Purity≥97% by HPLC
      SolubilityDMSO (10 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesKnockaert, M., et al. 2004. Oncogene 23, 4400.
      Polychronopoulos, P., et al. 2004. J. Med. Chem. 47, 935.
      Meijer, L., et al. 2003. Chem. Biol. 10, 1255.

      Produits & Applications associés

      Suggested Product

      Référence Description  
      361550 GSK-3 Inhibitor IX - CAS 667463-62-9 - Calbiochem Prix & Disponibilité
      361552 InSolution™ GSK-3 Inhibitor IX - CAS 667463-62-9 - Calbiochem Prix & Disponibilité

      Catégories

      Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Protein Phosphorylation / Dephosphorylation > Glycogen Synthase Kinase (GSK) Inhibitors