Millipore Sigma Vibrant Logo

01-106 FGF-2 / basic FGF Protein, Human recombinant

View Products on Sigmaaldrich.com
01-106
25 µg  
Le prix n'a pas pu être récupéré
La quantité minimale doit être un multiple de
Maximum Quantity is
À la validation de la commande Plus d'informations
Vous avez sauvegardé ()
 
Demander le prix
Disponibilité limitée
Disponibilité limitée
En stock 
Interrompu(e)
Disponible en quantités limitées
Disponibilité à confirmer
    Pour le restant : Nous vous tiendrons informé
      Pour le restant : Nous vous tiendrons informé
      Nous vous tiendrons informé
      Contacter le Service Clients
      Contact Customer Service

       

      Contacter le Service Clients

      Aperçu

      Tableau de caractéristiques principal

      Key ApplicationsSpeciesSource
      CULTHuman Recombinant DNA expressed in yeast (S. cerevisiae).
      Description
      Catalogue Number01-106
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionFGF-2 / basic FGF Protein, Human recombinant
      Product Information
      PresentationLiquid in PBS, pH 7.4, containing 0.5% BSA and 0.1% CHAPS.
      Quality LevelMQ100
      Applications
      ApplicationThe FGF-2 / basic FGF Protein, Human recombinant is available in a 25 µg format.
      Key Applications
      • Cell Culture
      Biological Information
      SourceRecombinant DNA expressed in yeast (S. cerevisiae).
      Entrez Gene Number
      Entrez Gene SummaryThe protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
      Gene Symbol
      • FGF2
      • Prostatropin
      • BFGF
      • prostatropin
      • HBGF-2
      • FGFB
      Purification MethodHeparin-Sepharose™ chromatography
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P09038 # The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors.
      SIZE: 155 amino acids; 17254 Da
      SUBUNIT: Monomer. Interacts with CSPG4 and FGFBP1. Found in a complex with FGFBP1, FGF1 and FGF2.
      SIMILARITY: SwissProt: P09038 ## Belongs to the heparin-binding growth factors family.
      MISCELLANEOUS: This protein binds heparin more strongly than does aFGF.
      Stem Cell Type
      • Human Embryonic Stem Cells
      • Neural Stem Cells
      • Epithelial Cells
      • Mesenchymal Stem Cells
      • Pancreatic Stem Cells
      • Induced Pluripotent Stem Cells
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by Biological Activity Assay. Cultures of fetal bovine heart endothelial (FBHE) cells grown for five days in RD medium containing FBS, heparin, and FGF-2 showed more cells than cultures of FBHE cells grown in same medium without FGF-2.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Packaging Information
      Material Size25 µg
      Global Trade Item Number
      Référence GTIN
      01-106 04053252332869