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MABE901 Anti-TAF15 Antibody, clone 4D71

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MABE901
100 µg  
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      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, ICCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABE901
      DescriptionAnti-TAF15 Antibody, clone 4D71
      Alternate Names
      • TATA-binding protein-associated factor 2N
      • 68 kDa TATA-binding protein-associated factor
      • TAF(II)68
      • TAFII68
      • RNA-binding protein 56
      Background InformationTAF15, also known as TATA-binding protein-associated factor 2N, or 68 kDa TATA-binding protein-associated factor, or TAF(II)68, TAFII68, or RNA-binding protein 56, and encoded by the gene TAF15/RBP56/TAF2N, is a RNA and ssDNA binding protein important in transcription initiation. TAF15 aligns with the RNA polymerase II (Pol II) multiprotein complex that together with other proteins like TBP initiates transcription. TAF15 is ubiquitously expressed, and TAF15 shuttles from the nucleus to the cytoplasm upon activation; methylation of TAF15 appears to guide nuclear localization and transcriptional activity. Translocations involving the TAF15 gene may play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene are associated with amyotrophic lateral sclerosis (ALS) diseases.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgG1κ in buffer containing PBS with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-TAF15 Antibody, clone 4D71 is an antibody against TAF15 for use in western blotting & ICC.
      Key Applications
      • Western Blotting
      • Immunocytochemistry
      Application NotesImmunocytochemistry Analysis: A 1:500 to a 1:1,000 dilution from a representative lot from an independent laboratory detected TAF15 in HeLa cells.
      Biological Information
      ImmunogenRecombinant protein corresponding to human TAF15.
      Clone4D71
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • TAF15
      • RBP56
      • TAF2N
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~68 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in HeLa cell lysate.

      Western Blotting Analysis: 0.5 μg/mL of this antibody detected TAF15 in 10 μg of HeLa cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      MABE901 04053252944444

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      Catégories

      Life Science Research > Antibodies and Assays > Primary Antibodies