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ABN642 Anti-LRRTM1 Antibody

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ABN642
100 µg  
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      Tableau de caractéristiques principal

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M, HWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABN642
      DescriptionAnti-LRRTM1 Antibody
      Alternate Names
      • Leucine-rich repeat transmembrane neuronal protein 1
      Background InformationLeucine-rich repeat transmembrane neuronal protein 1 (LRRTM1) exhibits strong synaptogenic activity that is restricted to excitatory presynaptic differentiation that acts at both pre- and postsynaptic levels. LRRTMs are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Each LRRTM protein is a type I transmembrane containing ten extracellular leucine-rich repeats and a short intracellular tail and has a developmentally regulated pattern distinct from all others. LRRTM1 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-LRRTM1 Antibody detects level of LRRTM1 & has been published & validated for use in LRRTM1.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: 5 μg/mL from a representative lot detected LRRTM1 in human brain tissue.
      Biological Information
      ImmunogenKLH-conjugated synthetic peptide corresponding to the C-terminus of human LRRTM1.
      EpitopeC-terminus
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Mouse
      • Human
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • LRRTM1
      • UNQ675/PRO1309
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~70 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in mouse brain tissue lysate with and without blocking peptide.

      Western Blotting Analysis: 1 μg/mL of this antibody detected LRRTM1 in mouse brain tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      ABN642 04053252946646