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ABC501 Anti-EDG3 Antibody

Anti-EDG3 Antibody is an antibody against EDG3 for use in Western Blotting and Immunohistochemistry.

Anti-EDG3 Antibody : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: S1PR3, EDG3 UniProt Number: Q99500
ABC501
100 µg  
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      Tableau de caractéristiques principal

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABC501
      DescriptionAnti-EDG3 Antibody
      Alternate Names
      • EDG3
      • Sphingosine 1-phosphate receptor 3
      • S1P receptor 3
      • S1P3
      • Endothelial differentiation G-protein coupled receptor 3
      • Sphingosine 1-phosphate receptor Edg-3
      • S1P receptor Edg-3
      Background InformationEDG3, also known as Sphingosine 1-phosphate receptor 3, S1P receptor 3 or S1P3 or Endothelial differentiation G-protein coupled receptor 3 or Sphingosine 1-phosphate receptor Edg-3 or S1P receptor Edg-3, and encoded by the gene name S1PR3 or EDG3, EDG3 is a member of the EDG family of receptors, which are G protein-coupled receptors. It has been identified as a functional receptor for sphingosine 1-phosphate (S1P) and likely contributes to the regulation of angiogenesis and vascular endothelial cell function.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ300
      Applications
      ApplicationAnti-EDG3 Antibody is an antibody against EDG3 for use in Western Blotting and Immunohistochemistry.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected EDG3 in human kidney and human liver tissue.
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to the C-terminus of human EDG3.
      EpitopeC-terminus
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Human
      Species Reactivity NoteHuman. Predicted to react with Feline based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • S1PR3
      • EDG3
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~52 kDa observed. The calculated molecular weight of this protein is 42 kDa, but can be observed at ~52 kDa due to high glycosylation (Magrassi, L., et al. (2010). Cancer Letters. 290(1):36-42). Uncharacterized band(s) may appear in some lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in Caco-2 cell lysate.

      Western Blotting Analysis: 0.5 µg/mL of this antibody detected EDG3 in 10 µg of Caco-2 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      ABC501 04055977151725

      Documentation

      Anti-EDG3 Antibody Certificats d'analyse

      TitreNuméro de lot
      Anti-EDG3 - 3397944 3397944
      Anti-EDG3 -Q2559136 Q2559136

      Références bibliographiques

      Aperçu de la référence bibliographiqueNº PubMed
      Cancer letters
      Magrassi, L; Marziliano, N; Inzani, F; Cassini, P; Chiaranda, I; Skrap, M; Pizzolito, S; Arienta, C; Arbustini, E
      Cancer letters  290  36-42  2009

      Afficher le résumé       		19748727 19748727

      Brochure

      Titre
      NPI Flyer- Epigenetics and Nuclear Function Feature

      Informations techniques

      Titre
      White Paper: Further considerations of antibody validation and usage.